According to a press release on the topic, 60 subjects with insomnia were randomized in a 2:1 ratio to receive either KSM-66 in a 300mg dose twice daily or an identical placebo, both for a period of 10 weeks. Participants monitored rest and activity patterns through sleep logs, self-reporting, and actigraphy.
Researchers found statistically significant improvements in sleep quality in terms of sleep onset, latency, total sleep time, wake after sleep onset, total time in bed, sleep efficiency, subjective sleep quality assessment, mental alertness on rising, and the Pittsburgh sleep quality index. Those who consumed KSM-66 also saw a significant reduction in stress, a finding consistent with several previous studies that showed that KSM-66 significantly reduced the concentration of the stress hormone cortisol in the blood.
Related: SOS for Stressed and Tired Ashwagandha Improves Memory and Cognitive Function in Study Study: Resveratrol Displays Anti-Stress EffectsMedicine Hunter Christopher Kilham, an ethnobotanist who served for 14 years as Explorer in Residence at the University of Massachusetts, Amherst, said in the release: “The new study corroborates the use of Ashwagandha root extract as a first-class adaptogen that helps promote restful sleep and reduce anxiety. We know that Americans are not getting enough sleep. Ashwagandha offers a simple, safe and natural way to achieve deep sleep for badly needed rest and repair, without drowsiness or negative effects. You simply do not need to resort to potentially harmful or addictive drugs to achieve healthy sleep.”
Kartikeya Baldwa, CEO of Ixoreal Biomed, creators of KSM-66, added: “Sleep is of course critical to well-being and healthy functioning. Published research has associated insomnia with chronic diseases such as obesity, type 2 diabetes, cardiovascular disease, neurological issues, mood swings, and increased mortality.”