Active Lifestyle

Akay Bioactives - Capsifen®

Capsifen® is a patented red chili pepper extract (Capsicum annum) standardized for effective and comfortable delivery of capsaicinoids. Powered by FenuMat®, it offers a pungency-free, slow-release formula that enhances bioavailability by 19x. Backed by two clinical studies, Capsifen supports thermogenesis, fat metabolism, appetite control, and endurance. Its proven safety and efficacy make it an ideal solution for weight management and sports performance formulations. www.akaybioactives.com

---

Applied Food Sciences - AmaTea® Max Organic Guayusa Extract

AmaTea® Max comes from Guayusa (Ilex guayusa), hailed as an Amazonian “super leaf” thanks to exceptional antioxidant properties and unique caffeine content. Its patented extraction process enhances the plant’s naturally occurring compounds to provide a nootropic ingredient that delivers a bright, balanced, and cognitively uplifting energy experience perfect for an active lifestyle. Numerous peer-reviewed journals have published articles on this ingredient’s efficacy and safe use. In addition, AmaTea® Max organic guayusa is USDA certified organic, FDA “no questions” GRAS for safe use in food and beverages, and sustainably grown in the Amazon, supporting thousands of indigenous farming families. www.appliedfoods.com

---

Arjuna Natural - Rhuleave-K®

Feel relief at the speed of light with Rhuleave-K®. Produced using patented SPEEDTECH® technology by Arjuna Natural, Rhuleave-K® is a unique blend of turmeric extract, boswellia extract, and black sesame seed oil that has been studied to promote a healthy inflammatory response in individuals with active lifestyles. A clinical study involving 200 participants, Rhuleave-K® effectively relieved exercise-induced musculoskeletal inflammation within approximately 3 hours, with an onset of action as early as 1 hour. In a women-focused clinical trial, Rhuleave-K® has also been shown to ease menstrual discomfort in as little as 30 minutes. This NSF-certified ingredient is the perfect addition to any workout supplement. www.arjunanatural.com

---

ChicoBag® - Original rePETe™ + Refine™

The ChicoBag® Original rePETe™ + Refine™ showcases one of the most sustainable fabrics in the reusable bag category. Made from 100% post-consumer recycled plastic bottles and dyed using the Refine™ solution (waterless) dye process, this fabric sets a new standard for environmental responsibility. Compared to traditional dyeing methods, it uses 89% less water, emits 63% less CO₂, and consumes 60% less energy—all while eliminating harmful plastic coatings. By combining circular materials with waterless color, rePETe™ + Refine™ proves that sustainability isn't a compromise, it's a design advantage. Watch the rePETe™ + Refine™ video to learn more. www.chicobag.com

---

Clasado Biosciences - Bimuno® GOS

Putting gut health at the heart of sports nutrition, Bimuno® GOS is a clinically backed prebiotic ingredient designed to support active health formulations. Clinically effective from just 2.75g daily, it delivers fast-acting gut microbiome support, shown to reduce exercise-induced GI symptoms and the duration of respiratory issues in elite athletes. The ingredient supports gut barrier integrity, immune resilience and recovery, key for training consistency. It integrates easily into powders, beverages, and gummies, with strong stability and tolerability. Backed by over 125 publications and 20+ clinical studies, it offers sports nutrition formulators a low-dose, high-impact tool for developing next-generation active lifestyle products. www.clasado.com

---

Ennature Biopharma - Xanthogreen®

Xanthogreen® is a clean label ingredient from marigold flowers that has been clinically studied to help boost your eye health with visible effects in as little as Week 4 onwards. Formulated with proprietary technology platform, SCEMOD™ (Super Critically Enabled Molecular Optimal Dispersion) facilitating better absorption and the bio efficacy thereof. Xanthogreen® exhibits enhanced solubility by 1000X - up to 20%, compared to conventional lutein, which is only 0.02%. Xanthogreen® is clinically studied to improve macular pigment optical density to an extent of 43% and contrast sensitivity to an extent of 51%. www.ennaturebiopharma.com

---

Gencor - ActivAMP®

ActivAMP® is a patented extract of Gynostemma pentaphyllum that has been clinically proven to support weight management and boost aerobic performance. It activates AMPK, the body’s “master metabolic regulator,” which encourages fat breakdown and improves glucose absorption. In a groundbreaking clinical study, ActivAMP increased VO₂ max and endurance performance by about 4% during a 20 km time trial. Mechanistic data confirmed elevated mitochondrial respiration and lowered muscle ACC and plasma leptin levels. Supported by both preclinical and clinical evidence, ActivAMP provides a potent, natural option for metabolic health and cardiorespiratory fitness. www.gencorpacific.com

---

KSM-66 - Ashwagandha®

KSM-66 Ashwagandha® is the most clinically studied Ashwagandha with 50+ trials and featured in over 4500 products, including those from major sports brands like Optimum Nutrition, MyProtein, MuscleTech, GNC, etc. KSM-66 Ashwagandha has been extensively studied in over 19 randomized, double-blind, placebo-controlled studies focused exclusively on sports nutrition and active lifestyles. KSM-66 demonstrated significant improvements in muscle strength, size, endurance, testosterone, and recovery in healthy adults. Endorsed by major athletes like Phil Heath, Hany Rambod and Olympic medalists, KSM-66 is backed by 46+ quality certifications, including BSCG Certified Drug-Free and Informed-Ingredient, confirming its safety for use in sports supplements. www.ksm66ashwagandhaa.com 

---

Maolac - Super Colostrum

Maolac Super Colostrum is the world's first bovine colostrum meticulously optimized for human compatibility, representing a significant advancement in bio-supplementation. Boasting an exceptional 75%+ protein content and a remarkable 95%+ structural and functional similarity to human breast milk, its unique combination of human-like proteins ensures profound physiological recognition and utilization. This advanced formulation delivers 7x greater efficacy than generic colostrum in a potent 140-mg dose. Essentially, Maolac Super Colostrum delivers the full spectrum of colostrum's benefits, but with significantly enhanced biological impact. www.maolac.com

---

HTBA - MecobalActive®

MecobalActive® is HTBA’s proprietary form of methylcobalamin that is bioidentical and active. Thanks to our patented green manufacturing processes, MecobalActive® is precisely engineered to get to work quickly and effectively in the body. MecobalActive® delivers cognitive and physical performance benefits—even for healthy, active individuals as our new and available scientific data can support. MecobalActive® has higher purity and efficacy, less water, (higher concentration), increased absorption and bioavailability and a longer shelf life.
Rethink B12: MecobalActive® is a new dimension in mental and physical performance. www.htba.com 

---

Nuritas - PeptiStrong®

Everything packaged is high in protein these days. The benefits are undeniable, but at what cost? Taste, texture and nutrition may be compromised. Introducing PeptiStrong®, a clinically studied plant peptide ingredient from fava beans discovered by Nuritas' AI Magnifier that boosts protein's effect 2x. It's validated by 3 human clinical trials showing:

• 2x muscle energy
• 2x muscle power
• 2x muscle recovery

2.4g is suitable in formats like bars, shakes, milk, pasta, powders and more.
While brands battle over protein grams, innovators can optimize for taste and more. Design the best protein experience for consumers today with PeptiStrong®. www.nuritas.com 

---

Nutrition21 - Nitrosigine®

Nitrosigine® is the superior nitric oxide booster, and the secret to whole body optimization. A patented complex of Bonded Arginine Silicate, Nitrosigine is clinically studied and proven to boost nitric oxide production for improved blood flow, supporting oxygen and nutrient delivery, healthy working muscles and better cognitive performance. Nitrosigine’s clinically backed efficacy and rapid action are supported by over 30 studies, including 8 clinical trials, and can be formulated into a range of healthy lifestyle products including tablets, capsules, powders, beverages, and bars. www.nutrition21.com 

---

NXT USA - TamaFlex™

TamaFlex™ is redefining the joint support and active nutrition market with its fast-acting, plant-based support. Three human clinical trials with 300+ participants show 250 mg TamaFlex lead to results starting in only five days. This market-leading “5 Days to Relief” message has brands using that front-of-pack claims language. This includes Tylenol, which launched its first supplement SKUs ever using TamaFlex as hero ingredient. Schiff’s Move Free, from Reckitt Benckiser, as well as top-selling animal supplement company Platinum Performance, also launched supplements featuring TamaFlex in 2025. Our winning comprehensive science approach includes patient questionnaires, physician assessments, biomarker testing, and physical performance. www.nxt-usa.com 

---

PLT Health Solutions - cellflo6®

Have you heard about cellflo6® yet? It’s getting a lot of word of mouth from athletes needing top performance. Phil Heath, a 7-time Mr. Olympia said: “cellflo6 fuels my intense training, enables faster recovery, and delivers an outstanding pump that is second to none.”
cellflo6 is a gallate-enhanced oligomer extract sourced from green tea (Camellia sinensis) that delivers endurance, exercise recovery, blood flow/circulation and non-stim energy in beverages, supplements and more. A survey of men who worked out regularly using cellflo6 for over 6 months showed that 84% felt increased endurance during workouts and 80% felt stronger and more capable during workouts. www.plthealth.com 

---

Puredia - CyanthOx™

CyanthOx™: Strongest Antioxidant for Anti-Aging. CyanthOx™ is Puredia’s potent antioxidant blend featuring proanthocyanidins, polyphenols, and bioflavonoids from premium sea buckthorn berries. With an impressive ORAC value of 895,281 μmol TE/100g—nine times stronger than grape seed extract—CyanthOx™ targets multiple hallmarks of aging, including mitochondrial dysfunction, stem cell exhaustion, cellular senescence, chronic inflammation, and dysbiosis. Clinical studies confirm CyanthOx™ enhances critical circulating stem cell activity by over 40%, improving tissue regeneration and cellular vitality. It significantly boosts mitochondrial membrane potential by 69%. CyanthOx™ also effectively reduces markers of chronic inflammation, lowering TNF-α by 33%, IL-6 by 57%, and VEGF by 29%. www.puredia.com 

---

SD Head USA - Actiserine™

Actiserine™: A New Gold Standard for Brain Health. Shankar Nutricon's Actiserine™ is a clinically proven breakthrough in cognitive support—delivering over 3X the absorption of conventional Phosphatidylserine (PS). This next-generation formula combines PS with catechins and arabinose in a proprietary nanocarrier system, enabling enhanced bioavailability, superior nutrient uptake, and longer-lasting brain benefits. In a double-blind clinical study, Actiserine™ achieved 2.8x higher peak concentration and a 15-hour half-life, all without adverse effects. Whether supporting memory, focus, or healthy aging, Actiserine™ works smarter and harder—raising the bar for cognitive nutrition. It’s not just an improvement—it’s a revolution in brain health. www.shankarnutricon.com 

---

Seipel Group - Urox®

Bladder accidents, urgency and frequency stop people being active. From the young, elite female athletes where 52% have incontinence impacting their sport (career-ending for 5%), to the more than half of older individuals that stop their gym, tennis or golf because their bladder (and embarrassment) won’t hold. Urox® is a natural, clinically proven formula that restores bladder control so people can move confidently and actively through life. 90% of users experience real improvements with less bladder accidents, frequency and urgency to regain freedom to exercise, socialize, and sleep uninterrupted. It’s a trusted solution supporting healthy aging, physical movement, and emotional wellbeing. www.seipelgroup.com 

---

TSI - PEAK ATP®

PEAK ATP® is a patented and clinically validated form of adenosine 5’-triphosphate disodium that helps power your body at the cellular level. PEAK ATP® provides functional energy and potentiates the role of ATP in the body, it supports muscular strength, endurance, and recovery—whether you're exercising, staying active outdoors, or simply managing a busy lifestyle. Human studies show benefits such as improved power output, reduced muscle fatigue, and better blood flow—all without the use of stimulants. PEAK ATP® is ideal for active individuals of all levels seeking to stay energized, strong, and physically capable—both during workouts and throughout daily movement. www.peakatp.com

---

Sleep/Stress Support

Activ'Inside - Safr’Inside™

Safr’Inside™, a patented, natural saffron extract with the highest safranal concentration (0.2% HPLC), offers clinically proven support for sleep health. Already well-established for its role in emotional balance and stress management, Safr’Inside™ enters the sleep category with robust scientific backing. Two clinical studies confirmed that this full-spectrum saffron extract significantly improves sleep quality by acting on the gut–sleep–brain axis—a vital pathway connecting gut microbiota, mood regulation, and restorative sleep. These studies are the first to evaluate Safr’Inside™ in gummy format and at two different doses (20 mg and 30 mg), with measurable improvements in only 21 days. www.activinside.com 

---

Akay Bioactives - ThymoDream™

ThymoDream™ is a patented and unique black cumin seed extract (Nigella sativa) standardized to deliver potent bioactives known as thymoquinones. Produced with a unique, proprietary cold-press technology, designed to preserve high levels of bioactives without the use of heat or solvents. With four compelling clinical studies behind it, ThymoDream manages occasional sleeplessness, stress, and immune health. Additionally, ThymoDream‘s safety, efficacy, and unique mechanism of action have been substantiated to balance natural melatonin and cortisol levels in the body. Discover the power of ThymoDream, a clinically substantiated, plant-based solution for dreamy nights, calm days and holistic wellness. www.akaybioactives.com 

---

Arjuna Natural - Shoden® Ashwagandha

Unwind faster and for longer with Shoden® Ashwagandha. The world’s most potent and bioavailable ashwagandha extract has been clinically demonstrated in over 8 human clinical trials to help relieve stress, improve mood, enhance sleep quality, promote vitality, and support overall health at a low dose of 60 mg/day. Its most recently published study, Shoden, showed a 66% decrease in serum cortisol levels and a 59% decrease in feelings of anxiety. Shoden is also clinically validated to increase sleep quality by 73%. Shoden’s low-dose efficacy, neutral taste profile, and clean label features make it the perfect addition for any dietary supplement, functional beverage, or food. www.arjunanatural.com 

---

Ethical Naturals - AlphaWave®

AlphaWave® is a highly purified L-Theanine produced by a proprietary fermentation and purification process in a facility that has been fully audited, cGMP and ISO/FSSC-22000 certified by SGS and inspected by US-FDA. It is supplied though ENI's NSF certified distribution and testing facility. Three clinical trials support the following S/F claims for AlphaWave®: Helps relax without drowsiness, promotes mental clarity and focus, Reduces nervous tension. AlphaWave® is GRAS affirmed, approved by the Australian Therapeutic Goods Authority (TGA) and has a Canadian NPN number. AlphaWave®'s consistent quality and experiential stress-relief make it a leading ingredient in our stressful times. www.ethicalnaturals.com

---

Gateway Health Alliances - Somnoril™

Somnoril™ is a patented, clinically validated extract of Dichrostachys glomerata that supports restorative sleep, reduces stress, improves mood, and promotes healthy weight. In two recent randomized, placebo-controlled clinical trials, Somnoril™ significantly improved sleep quality and duration, reduced time to fall asleep, increased deep sleep, and boosted daytime activity. Participants also reported fewer food cravings, less perceived stress, improved mood, and enhanced quality of life. Backed by six clinical studies involving over 600 subjects, Somnoril™ offers brands a science-backed, multifunctional solution that addresses the powerful connection between sleep, stress, and metabolic wellness at a 300 mg daily dose. www.ghainc.com

---

K. Patel Phyto Extractions - Ocitum™

Ocitum™ is a standardized Holy Basil (Ocimum) extract, clinically proven for stress management and sleep support. It is standardized for key active ingredients Ursolic Acid, Eugenol and Rosmarinic Acid, which ensures consistent potency and quality. Sourced responsibly and committed to sustainable farming, Ocitum is a safe and reliable option for those seeking natural solutions for stress and sleep formulations. Relax, unwind and sleep naturally with Ocitum. www.phytoextractskp.com 

---

KSM-66 - Ashwagandha®

KSM-66 Ashwagandha® is the most clinically studied Ashwagandha with 50+ trials and featured in over 4500 products in over 65 countries, making it the largest natural product ingredient brand in the world. KSM-66 has been evaluated in 12+ clinical trials in humans and 5+ studies in pets and was found to be effective in reducing cortisol levels, perceived stress scores, anxiety, and improving sleep onset latency, sleep efficiency, and total sleep time. The most unique amongst these is a groundbreaking clinical study using KSM-66 with over 1,000 subjects across five continents—Asia, North America, Australia, Europe, and Africa—evaluating KSM-66's effect on stress and cortisol levels. www.ksm66ashwagandhaa.com 

---

Maypro - Venetron®

Venetron® is a low-dose natural solution for stress and sleep support, offering versatility in formulation and delivery formats for the innovative dietary supplement industry. Available in both standard and water-soluble formats, it provides flexibility for formulators looking to customize product delivery or adapt to evolving consumer preferences, whether in gummies, jellies, RTDs, powders, or other novel forms beyond traditional capsules and tablets. In addition to its adaptability, Venetron® is highly cost-effective, requiring only a low clinical dose of 50mg to achieve impactful results. This allows for efficient formulation without adding unnecessary bulk or expense. Supported by strong safety and human clinical data, Venetron® ensures confidence in both efficacy and reliability at such a low dosage. www.maypro.com 

---

Natural Remedy - Holixer™

Holixer™ is a clinically validated extract of Holy Basil (Ocimum tenuiflorum), utilizing proprietary Bioactive Optimization Technology (B.O.T.™). Holixer™ delivers a potent Ocimum Bioactive Complex (OBC™) standardized to over 5% bioactives. At a daily dose of 250 mg, Holixer™ has demonstrated significant reductions in stress and cortisol levels, and improvements in sleep quality, as evidenced by a randomized, double-blind, placebo-controlled clinical trial. This non-habit-forming, water-soluble adaptogen is suitable for various formulations like gummies, capsules, and sachets, offering a natural solution for stress and sleep support. www.naturalremedieshumanhealth.com 

---

Nuritas - PeptiSleep™

Millions of people still struggle with sleep and feeling at their best the next day. Introducing PeptiSleep™, the first natural plant peptide ingredient from brown rice discovered by Nuritas' AI Magnifier and validated with a human clinical trial showing comprehensive sleep support across all phases of the sleep cycle. It's measurable using your sleep tracking wearables, and also suitable in formats like powders, RTD beverages, health shots, chews, gummies and capsules. With 250 mg 30 minutes before bed, you will see that it can:
•Increase deep sleep time by 17% on average
•Improve sleep quality including adding 40 more minutes of sleep on average
•Help you wake up feeling rested
Good sleep is within reach. Help your consumers get there today with PeptiSleep™. www.nuritas.com 

---

Nutraland - Somato®

Somato® is an upcycled, sustainable tomato fruit extract that delivers a natural source of phytomelatonin—offering a whole-food derived, clean-label alternative to synthetic melatonin. In a human clinical trial, participants fell asleep 33% faster with Somato® and experienced improvements in sleep efficiency and emotional well-being, along with better scores in energy/fatigue, pain, social functioning, and physical function compared to baseline. Research also suggests that phytomelatonin may be a safer option than synthetic melatonin and could offer additional potential benefits due to its plant matrix—making Somato® a compelling, natural solution for sleep, recovery, and holistic well-being. www.somato.cc 

---

Nutrition21 - EverZen™

EverZen™ is a premium, plant-based ingredient providing a fresh & differentiated approach to mood & stress, helping ease the mind and achieve mental balance. EverZen™ is clinically shown to help promote a positive mood, help with occasional anxiety, and support a healthy stress response. It’s standardized to a novel, naturally occurring, and potent bioactive, 6-MBOA, offering powerful benefits for mental & emotional wellbeing. EverZen works within the brain to ease the mind and balance the body through a unique dual-action approach. With a low dose and supported by two clinical studies, EverZen is suitable for a range of supplement formats. www.nutrition21.com 

---

OmniActive Health Technologies - Sleeproot Valerian Extract

Just 200 mg per day of Sleeproot valerian extract has been clinically shown to support different aspects of sleep quality such as time to fall asleep and actual time asleep, with an increase in sleep duration starting on DAY 1 of supplementation. Non-hormonal, melatonin-free Sleeproot stands out by delivering low-dose efficacy with a high active content of 2% valerenic acid, making it ideal for modern delivery formats where traditional valerian extracts have notoriously faced organoleptic challenges. This includes applications such as gummies and ready-to-mixes, as well as conventional forms like tablets and capsules. www.omniactives.com 

---

PLT Health Solutions - Serezin™ Restorative Sleep + Pain Relief

Serezin™ Restorative Sleep + Pain Relief has been clinically demonstrated to help people get to sleep faster and easier, improve their quality of sleep and help them wake easier, more alert and in a better mood. It works by reducing daily aches and pains that prevent quality sleep. Unlike melatonin and other conventional sleep ingredients, it does not induce sleep per se. Instead, it provides the conditions that allow for faster, better and more restorative sleep. It performs as a standalone ingredient or as a ‘bolt on’ in multicomponent sleep formulations by adding benefits achieved through its unique mechanism of action. www.plthealth.com

---

PLT Health Solutions - Vanizem™

For people trying to find their chill and get better sleep, fast-acting Vanizem™ supports positive mood, improves sleep quality and helps manage mild day-to-day stress and anxious feelings. Want it fast? Supplementation with Vanizem™ was shown to improve sleep quality scores after just 1 dose. Its patent-pending extract targets the endocannabinoid system by inhibiting fatty acid amide hydrolase (FAAH), thereby maintaining anandamide levels, which may regulate mood and anxiety without psychoactive or sedative effects. In a recent clinical study, Vanizem™ was found to significantly improve self-reported perceptions of reducing total mood disturbance score in a dose-dependent manner. www.plthealth.com

---

Probi - Mental Health by Probi®

Mental Health by Probi® features the proprietary strain Lactiplantibacillus plantarum HEAL9®, clinically shown to improve sleep quality and reduce stress. Backed by multiple randomized controlled trials, HEAL9® significantly enhances restful sleep, lowers morning cortisol levels, and promotes a balanced stress response. Its psychobiotic effects are rooted in the gut-brain axis, with studies demonstrating improvements in mood, cognitive performance, and resilience. With sleep and stress among the top global health concerns, Probi offers a clinically substantiated, formulation-ready solution that empowers supplement brands to address consumer demand with science-first innovation and measurable mental wellness benefits. www.probi.com 

---

Sempera Organics - SO-DSX1®

SO-DSX1® is a clinically validated organic Lion’s Mane (Hericium erinaceus) blend from Sempera Organics, sustainably produced using proprietary strains and precision mycology. It delivers a full spectrum of bioactive compounds that support cognitive function and mood. In a randomized, placebo-controlled trial published in Nutrients, a single 1.8 g dose improved cognitive reaction time within 60 minutes, with greater cognitive and stress-reduction benefits after 28 days. This is the first known study to show both rapid and sustained effects of lion’s mane in healthy young adults, positioning SO-DSX1® as a powerful ingredient for cognitive health and stress support. www.semperaorganics.com 

---

TriNutra - ThymoQuin®

ThymoQuin® is the only premium, USP compliant black seed oil. In a double-blind, placebo-controlled clinical trial, ThymoQuin supplementation led to a 44% reduction in salivary cortisol—our primary stress hormone—after intense physical and psychological stress. This cortisol-lowering effect is crucial for promoting deeper, more restful sleep and supporting mood regulation. With its standardized 3% thymoquinone content and low free fatty acids, ThymoQuin helps rebalance the gut-brain axis, enhance recovery, and reduce the toll of chronic stress, offering a science-backed solution for stress resilience and restorative sleep. www.trinutra.com

---

Bone/Joint Health

Arjuna Natural - BCM-95® Turmeric Extract

Head, shoulders, knees, or toes, BCM-95® turmeric extract by Arjuna Natural has you covered. Published in 90 scientific publications and backed by over 45 human clinical trials, BCM-95® is the world’s safest and most clinically researched turmeric extract for joint health. This FDA GRAS, patented extract contains curcuminoids and essential oils naturally present in the turmeric rhizome, providing increased bioavailability, long-lasting benefits, and sustained activity in the body. In various joint health studies, BCM-95® has been shown to significantly improve WOMAC scores, joint stiffness, and joint function. Manufactured using 100% solar power, BCM-95® is good for the body and the planet. www.arjunanatural.com 

---

Ennature Biopharma - Maxicuma®

Maxicuma® is a clinically studied, clean label ingredient from turmeric, standardized to 40% curcuminoids that helps support in alleviating joint pain, stiffness, mobility and physical performance at an ultra-low dose of 100-250 mg/day. Formulated with proprietary technology platform, LIMAN™ (Lecithin based Liposomal Microencapsulation), Maxicuma® exhibits enhanced solubility delivering 172 folds higher levels of free curcumin in the human blood plasma than conventional curcumin extract, facilitating better absorption and the bio efficacy thereof. Maxicuma® allows brands to develop joint and mobility supplements for active adults, athletes, and healthy aging populations into formats like gummies, lozenges, chews, pills, RTD, beverages, etc. www.ennaturebiopharma.com 

---

Gnosis by Lesaffre - MyCondro™

MyCondro™ is the world’s first chondroitin sulfate produced through fermentation. This animal-free alternative delivers superior bioavailability compared to traditional animal-derived chondroitin sulfate.  With its exceptional purity level, MyCondro™ significantly reduces contamination risks associated with animal-sourced versions. This vegan ingredient has been clinically validated to effectively support joint health even at reduced dosages. The versatility of MyCondro™ allows for seamless integration into various joint health supplement formulations: capsules, tablets, instant beverages, protein powders, and many other formats. www.gnosisbylesaffre.com

---

Guzen Development - SCP-II®

SCP-II®: Salmon Collagen Proteoglycan Complex is our joint and skin health supplement and is the only ingredient on the market that contains both undenatured Type II Collagen and undenatured Proteoglycan. Unlike the collagen peptides, both undenatured Type II Collagen and undenatured Proteoglycan maintain important actives sites that are recognized by the body and leads to the inhibition of an auto-immune response that causes inflammation in the joints. These active sites are believed to be the mechanism behind SCP-II’s ability to decrease knee pain in subjects at a very small dose in a much more effective way than glucosamine. www.guzendevelopment.com 

---

IminoTech, Inc. - Q-actin™

Q-actin™ is a patented, clinically validated cucumber extract (Cucumis sativus) standardized to more than 1% ido-BR1, a rare iminosugar with a novel mechanism of action. In randomized clinical trials, Q-actin™ significantly improved joint comfort, mobility, and function compared to both placebo and glucosamine-chondroitin. Its ultra-low daily dose of just 20 mg enables convenient formulation across capsules, tablets, powders, and blends. Orally bioavailable and highly effective, Q-actin™ delivers consistent results and sets a new standard in natural joint support—making it an ideal choice for innovation-focused functional food, beverage, and supplement brands. www.iminotech.com 

---

Maypro - Mesoporosil®

Mesoporosil® is an innovative source of bioavailable silicon, addressing the limitations of conventional silicon ingredients. Although silicon is the second most abundant mineral on Earth, it is often overlooked despite its crucial role in maintaining the structure of connective tissues including bones, joints, and skin. It is an essential co-factor for collagen production and supports bone mineralization by stimulating osteoblast activity. Additionally, Mesoporosil® features mesoporous-sized pores, which significantly increase surface area for optimal interaction with intestinal tissues.www.maypro.com 

---

Microphyt - PhaeOptim™

PhaeOptim™ is a clinically proven microalgae-based ingredient that improves bone mineral density (+1.4%) in just 3 months—based on a robust clinical study conducted 100% on women. Designed for premenopausal women, it addresses bone fragility and reinforce bones before hormonal changes accelerate bone loss during menopause. Pre-menopause is a critical window to build and protect bone health, yet targeted support is still lacking. PhaeOptim™ delivers faster, more meaningful results than resistance training and outperforms gold-standard ingredients, offering a unique natural, sustainably produced and science-backed solution to help women improve bone strength, vitality, and independence as they age. www.microphyt.eu 

---

Nutrition21 - Celadrin®

Celadrin® is a proprietary complex of cetylated fatty acids that have been studied to provide joint health and skin health benefits. Celadrin® is made through a specialized manufacturing process that results in an ingredient blend with a defined, consistent mixture of the cetylated fatty acids. The fatty acids are easily absorbed both orally and topically, making their way into tissues and joints where they play a supportive role. Celadrin® is available in both powder and oil format to allow for formulation flexibility and also comes in both vegan and non-vegan forms. www.celadrin.com 

---

PLT Health Solutions - AprèsFlex® 5-Day Joint Support

AprèsFlex® 5-Day Joint Support has been clinically demonstrated to be effective with a super low 100 mg/day dose. It works fast, with enhanced comfort beginning at 5 days. And it gets better, supporting ongoing improvement in comfort, flexibility and physical function with no plateau seen even at 6 months. The new news on AprèsFlex is a breakthrough clinical study that shows support for cartilage health, where it improves the preservation and protection of our irreplaceable cartilage. It’s the powerful combination of short-term relief, long-term improvement and with cartilage benefits that makes AprèsFlex a must-see ingredient in the joint health category. www.plthealth.com 

---

Stratum Nutrition - NEM®

NEM® is a natural, food-sourced, complete joint health ingredient in a small 500 mg daily dose that provides greater formulation flexibility. Research reveals that NEM® supplementation can help reduce exercise-induced pain and stiffness and help protect cartilage against breakdown.* The NEM® matrix is predominantly protein (50-70%) and contains the glycosaminoglycans (GAGs) chondroitin sulfate, dermatan sulfate, keratan sulfate, and hyaluronic acid, as well as collagen types I, V, and X. www.stratumnutrition.com

---

TSI - GlucosaGreen®

GlucosaGreen® is a next generation glucosamine produced through a plant-based fermentation process—completely free from shellfish and animal byproducts. Backed by certifications like ISCC PLUS, Ecovadis, and ISO 14067, it offers a 70 % lower carbon footprint than traditional sources. It supports joint health, mobility, and cartilage integrity in aging and active populations. Vegan, non-GMO, allergen friendly, and suitable for kosher and halal formulations, GlucosaGreen® is manufactured in cGMP certified facilities with full traceability. Perfect for forward thinking joint support formulations targeting both human and pet health while aligning with eco conscious brand values. www.peakatp.com 

---

VeCollal® Type II – Move Freely, Naturally

VeCollal® Type II is the plant-based revolution in joint health. Designed to mimic human Type II collagen, it supports cartilage, reduces stiffness, and promotes smoother, more comfortable movement. 100% vegan and sustainably made, it delivers the benefits of traditional joint support—without animal ingredients. Backed by science, VeCollal® Type II helps active and aging consumers stay mobile, naturally. www.vecollal.eu 

---

Vegan Minerals – WholeCal™

WholeCal™ is a whole-food calcium ingredient derived from clinically supported red marine algae, offering bioavailable calcium, magnesium, and 70+ naturally occurring trace minerals and amino acids. While most traditional calcium supplements are made from rocks or synthetics that the body struggles to absorb, WholeCal™ delivers calcium in a natural matrix the body can readily utilize. This is critical for maintaining bone strength and joint mobility, particularly for women, who face an increased risk of bone loss with age. Sustainably harvested and minimally processed, this award-worthy ingredient sets a new standard in clean, effective bone and joint support. www.veganminerals.com

---

Heart Health

CoreFX Ingredients - OmegaFX™ 40V-TH Algal Oil Powder 150-75

Sourced from sustainable microalgae, this plant-based powder delivers a potent dose of EPA to support cardiovascular health—without the unpleasant taste of traditional omega-3s. It’s a breakthrough solution to a long-standing challenge: making omega-3s both palatable and stable. Each gram provides 150 mg of EPA and 75 mg of DHA, offering an EPA-rich profile to support heart health. Produced using low-temperature, nitrogen-rich drying with electrostatic energy, it protects nutrient integrity and sensory quality. This neutral-flavored, stable powder suits functional foods and supplements like drinks, chews, and gummies. Made in the U.S. with vegan-friendly encapsulation, OmegaFX™ delivers clean-label heart health support. www.corefxingredients.com

---

Ingredients by Nature - Sytrinol®

Diets rich in flavonoids continue to exhibit significant support for cardiovascular function. Sytrinol® is a double-patented blend of citrus and palm fruit flavonoid extracts with strong clinical evidence to support various markers of a healthy heart in just four weeks. The randomized, double-blind, placebo-controlled study demonstrated that with 270 mg/day, Sytrinol significantly modulated cholesterol levels (-27%), LDL cholesterol levels (-25%), the LDL: HDL ratio (-28%), and triglyceride levels (-31%). Sytrinol is vegan, Kosher certified, and commercially available in several dietary supplements. www.ingredientsbynature.com 

---

Kaneka - Ubiquinol®

Ubiquinol®, the active antioxidant form of Coenzyme Q10, is found throughout our cells, tissues, and organs. It is required for 95% of cellular energy (ATP) production and is essential for cellular function and antioxidant support, aiding physiological processes vital for cardiovascular health. Research has found that ubiquinol offers heart benefits by protecting LDL cholesterol from oxidation, which helps to maintain healthy blood flow, and by improving certain blood markers associated with heart health. Kaneka Ubiquinol® helps the heart by:
• Supporting the high-energy requirements of the heart
• Protecting cells from damage caused by oxidative stress
• Replenishing CoQ10 blood levels depleted by statin medications
•S upporting nitric oxide synthesis for vessel health and circulation. www.kanekanutrients.com 

---

Lycored - Lycomato⁶™

Lycomato⁶™ is Lycored’s flagship health extract harvested from a proprietary breed of freshly grown red ripe tomatoes and containing optimal concentrations of lycopene, phytoene, phytofluene, phytosterols, tocopherols, beta-carotene, and essential vitamins. Studies show supplementation with Lycomato⁶™ supports a healthy circulatory system by reducing inflammation and oxidative stress, lowering LDL cholesterol oxidation, and maintaining blood pressure and endothelial function, which plays an important role in the control of blood fluidity, platelet aggregation and vascular tone. In studies, Lycomato⁶™ has been shown to have high antioxidant properties and protect against cellular damage to slow the cellular aging process and support longevity. www.lycored.com 

---

PLT Health Solutions - MegaNatural-BP® Grape Seed Polyphenol

Grapes are great! They offer us so much. Here’s more. MegaNatural–BP® is a unique grape seed extract made in California USA from sustainably grown unfermented red and white varietal wine grape seeds. This clinically studied patented ingredient can help maintain healthy blood pressure regulation. One study showed improvement of blood pressure levels in just 2 hours after use! Clinical studies show the efficacy of MegaNatural–BP at 150-300 mg per day. Nearly 100% water-soluble with a neutral taste, MegaNatural–BP is ideal for use in supplements, functional foods, and beverages. It is certified non-GMO by the Non-GMO Verification Project. www.plthealth.com 

---

Probi - Metabolic Health by Probi®

Metabolic Health by Probi® features two proprietary probiotic strains—Lactiplantibacillus plantarum 299v (LP299V®) and Lacticaseibacillus paracasei 8700:2®—clinically shown to support multiple markers of cardiovascular health. Backed by robust human studies, this concept addresses healthy cholesterol levels, blood pressure regulation, insulin response, and inflammation. As metabolic health challenges rise globally, Probi delivers a science-forward solution that empowers brands to launch with confidence. With proven strain synergy, formulation expertise, and manufacturing support, Metabolic Health by Probi® offers a turnkey path to innovation in one of the most pressing and complex health categories today. www.probi.com 

---

Puredia - CardiOmegia™

CardiOmegia™: Synergistic Omega-7 and DHA Formulation for Metabolic Health. Delivering the highest concentration of omega-7 available for cardiovascular and metabolic support. Clinical studies show CardiOmegia™ significantly reduces inflammatory markers such as TNF-α by 26% and IL-6 by 48%. Notably, when combined synergistically with DHA, CardiOmegia™ further enhances these benefits—reducing TNF-α by up to 62% and increasing the beneficial anti-inflammatory cytokine IL-10 by 60%. This unique synergy between omega-7 and DHA helps improve insulin sensitivity, regulate lipid metabolism, and support healthy weight management, addressing key components of metabolic syndrome. Ideal for cardiovascular, metabolic, and sports nutrition supplements. www.puredia.com 

---

TriNutra - ThymoQuin®

ThymoQuin® black seed oil is redefining natural cardiovascular support. Clinically shown to significantly improve blood pressure in just six weeks, ThymoQuin’s unique 3% thymoquinone concentration with low free fatty acids delivers potent, bioavailable heart health benefits. This proprietary formulation demonstrated a measurable improvement in vascular function in healthy adults with results seen as early as 48 hours with 500 mg per day. www.trinutra.com

---

Cognitive Health

Aker Biomarine - Lysoveta®

Lysoveta® is the first commercially available lyso-phosphatidylcholine (LPC) ingredient of its kind proven to cross the blood-brain barrier, delivering key ingredients like EPA/DHA directly to the brain. It does this by enhancing omega-3 EPA/DHA uptake, supporting cognitive health in the form the brain needs (LPC) to perform at its best. Lysoveta is backed by 15 patents, NDI status in the US, and 12 preclinical studies, with a human clinical trial underway. As a breakthrough dietary ingredient crafted to support memory, mood, and cognitive performance for healthy brain aging, Lysoveta offers brands a powerful solution for developing cutting-edge brain health products. www.akerbiomarine.com 

---

Applied Food Sciences - MycoThrive™ Lion’s Mane Extract

MycoThrive™ Lion’s Mane is backed by a first-of-its-kind human clinical demonstrating its acute (i.e., single-dose) cognitive benefits, with significant results in as little as one-hour post-ingestion. MycoThrive™ Lion’s Mane is standardized to β-Glucans (1,3 / 1,6) with measurable levels of secondary active compounds. Its nootropic advantages are attributed to compounds like hericenones and erinacines, supporting Nerve Growth Factor (NGF) synthesis for cognitive benefits. MycoThrive™ Lion’s Mane has substantiated evidence to demonstrate that it can improve mental clarity, focus, working memory, complex attention, concentration, processing speed, and reaction time. In addition, it promotes emotional well-being and mood stability by elevating subjects’ feelings of happiness and “getting the most out of everything.” www.appliedfoods.com 

---

Bio-gen Extracts - Lute-gen®

Lute-gen® is a clinically studied, patented marigold extract standardized to 10 mg lutein and 2 mg zeaxanthin. It targets the Eye-Brain axis—a vital communication pathway linking visual input with cognitive performance—to support memory, learning, and neuro-visual function. Backed by global peer-reviewed research, Lute-gen® also shows evidence in reducing telomere shortening, a biomarker of biological aging. Trusted by global brands, it performs across formats like gummies and oral thin films. Sustainably sourced and clean-label (vegan, natural, Non-GMO, allergen-free), Lute-gen® is built on a foundation of equity, scientific integrity, and purpose—advancing cognitive health through innovation that is both inclusive and impactful. www.bio-gen.in 

---

CoreFX Ingredients - OmegaFX™ 30V-TH Algal Oil Powder 220DHA

OmegaFX™ 30V-TH Algal Oil powder delivers essential brain-supporting DHA in a shelf-stable, plant-based format. Designed to meet rising demand for vegan-friendly options, it offers a clean, fish- and dairy-free source of DHA—vital for brain development, cognitive performance, and early-life nutrition. With a remarkable 22% DHA concentration—one of the highest on the market—this formula supports peak cognitive function. Produced using a low-temperature, nitrogen-rich environment and electrostatic energy, it preserves nutrient integrity and sensory quality. This neutral-flavored, stable powder suits functional foods and supplements like prenatal chews, drinks, and gummies. Made in the U.S. with vegan encapsulation, OmegaFX™ supports clean-label cognitive health.www.corefxingredients.com 

---

FrieslandCampina Ingredients - Biotis® DHA Flex Powders

DHA is an omega-3 that provides multifaceted benefits such as supporting brain, eye, and cardiovascular health, plus recovery from exercise. Crafted with precision, Biotis® DHA Flex Powders are algae-derived microencapsulated DHA powders with superior clean taste without any fishy odor/taste. Designed to help brands offer consumers high-quality omega-3 products with multifaceted health benefits without compromising on taste, format or dietary preferences. This offers food, drink and supplement producers a solution with a neutral sensory profile and exceptional stability and solubility, in powder formats, enabling freedom of versatility in formulation options. www.biotis.com 

---

GC Rieber - VivoMega® Algal Oil

VivoMega® Algal Oils represents a new, plant-based, and highly potent source of Omega-3 EPA+DHA. Omega-3s are one of the most significantly studied ingredients to support cognitive health, memory, and mood. Research highlights their role in maintaining brain structure and promoting neurotransmitter function across all life stages. VivoMega stands out for its exceptional purity, quality, bioavailability, and sensory profiles, making it a superior solution for brain-focused formulations. As demand grows for sustainable, vegan-friendly cognitive support, VivoMega® Algal Oil meets consumer demand with potent, sustainable, and transparent products that exceed all international industry TOTOX requirements, including the GOED monograph and IFOS Criteria. www.vivomega.com 

---

Gencor - Levagen®+

Levagen+ is an innovative solution designed to meet the needs of today’s health-conscious consumers. It provides a safe, novel, clinically supported, natural, and practical option for improving cognitive health. According to published clinical data, Levagen+ has demonstrated significant positive effects on cognition, memory, mood, anxiety relief, relaxation, and sleep. It promotes the production of brain-derived neurotrophic factor (BDNF), which is essential for maintaining normal neuronal function and is associated with improved memory, learning, and cognitive abilities. www.levagenplus.com 

---

Gnosis by Lesaffre - Adonat®

Adonat® Premium SAMe is a top-quality, fermented form of S-Adenosyl-L-methionine, a vital compound supporting over 100 biochemical processes. As a powerful methyl donor, it promotes DNA stability, gene regulation, and synthesis of key cellular components. Backed by superior quality standards, Adonat® stands out as the only branded SAMe, offering flexible dosing, stabilized solutions and proven benefits for mood, cognitive function, liver detox, and joint health. Daily supplementation supports healthy aging, longevity, and overall well-being—making Adonat® a trusted ally in maintaining optimal health throughout adulthood, and across generations. www.gnosisbylesaffre.com 

---

KSM-66 - Ashwagandha®

KSM-66 Ashwagandha® is the most clinically studied Ashwagandha with 50+ trials and featured in 4500+ products in 65+ countries, making it the largest natural product ingredient brand in the world. For cognitive health, in both adults and children, 4 randomized, double-blind, placebo-controlled studies have demonstrated significant improvements in working and episodic memory, attention, executive function, and information processing. Additionally, in children with ADHD, KSM-66 reduced inattention, hyperactivity, anxiety, and sleep disturbances, with notable improvements in behavioral and emotional regulation. All studies confirmed safety and meaningful enhancements in cognitive performance, making KSM-66 one of the best-selling nootropic ingredients on the market. www.ksm66ashwagandhaa.com 

---

Microphyt - BrainPhyt™

BrainPhyt™ is a clinically proven microalgae extract that enhances cognitive function—including memory, executive function, attention, and vigilance—in older adults with age-related cognitive decline. In a 6-month study, it reduced CRP by 45%, reflecting up to 10 years of brain rejuvenation. Rich in omega-3s and fucoxanthin—a bioactive that crosses the blood-brain barrier—BrainPhyt™ lowers significantly inflammation and oxidative stress biomarkers (TNF-α, IL-6, lipid peroxidation…). Supported by two clinical and seven preclinical studies, it acts via Nrf2 and PPAR-α pathways. Produced with patented, sustainable technology, BrainPhyt™ is a low-dose, natural, and science-backed solution for cognitive function and healthy aging. www.brainphyt.com 

---

Myzel Organics - Full Spectrum Function Mushroom Powders

Myzel Organics delivers ancient ingredients for modern minds. Our full spectrum mushroom powders including Lion’s Mane, Reishi, Cordyceps, and Chaga are grown on nutrient rich sorghum at our net zero energy facility, using proprietary strains developed for potency and consistency. Trusted by forward thinking brands, Myzel mushrooms support clarity, focus, memory, and gut health. Each batch is crafted to fuel products with purpose, enhancing mental wellness while promoting sustainability and community well-being. In an era where cognitive and digestive performance matter more than ever, Myzel offers a natural, science-backed solution that helps people think clearly, feel balanced, and live fully. www.myzelorganics.com 

---

Nutraland - Miricell™

Miricell™ is an upcycled, sustainable rice germ extract rich in natural spermidine and other polyamine compounds. Human clinical research on Miricell™ demonstrated that it effectively increased markers of autophagy (the body’s cellular renewal process) and BDNF (a key cognitive wellness marker), while decreasing CRP (an inflammatory marker), VLDL cholesterol and triglycerides. Additional human clinical research showed that Miricell™: 1) improved cognitive function by 98% compared to placebo in subjects with mild cognitive dysfunction, 2) supported fuller, thicker hair while reducing shedding, and 3) promoted nail growth and strength – highlighting its potential as a multi-benefit solution for healthy aging and vitality. www.somato.cc 

---

Nutrition21 - nooLVL®

nooLVL® is a patented complex of Bonded Arginine Silicate and Inositol that offers consumers focus they can feel in as little as 15 minutes – without the side effects of stimulants. The combination of Bonded Arginine Silicate and Inositol work together as a one-of-a-kind ingredient supporting optimal brain performance. Backed by 3 clinical studies, nooLVL® is a safe and effective nootropic ingredient that helps improve focus, concentration, and memory – all while helping you feel more energized. nooLVL® can be formulated into a variety of cognitive health applications including tablets, capsules, powders, beverages, and bars. www.nutrition21.com 

---

OmniActive Health Technologies - enXtra Alpinia galanga extract

Clinically studied, caffeine-free enXtra is a proprietary extract of Alpinia galanga (aka Thai ginger), a spice long used in Asian cuisine. Multiple clinical studies have shown that 300 mg of enXtra supports attention and focus, as well as delivers up to five hours of mental energy and alertness without the crash or jitters associated with caffeine. Moreover, studies have shown that  enXtra does not affect heart rate, blood pressure, or sleep cycles.  enXtra helps power premium cognitive, sports nutrition, and hydration products with mental energy benefits you can feel! www.enxtra.com 

---

PLT Health Solutions - Nutricog® Cognitive Performance Complex

When it comes to creating brain performance products, Nutricog® Cognitive Performance Complex is like a great actor. It has such a broad range of ‘talent’ that it can carry an entire production by itself. At the same time, its individual qualities can help support other great ingredient performers. Clinical studies show that Nutricog® offers significant performance improvements in learning, memory, sustained attention, working memory and executive function. Increases in cognitive speed were seen concurrently with improvements in accuracy while multitasking. What’s your choice? Whether you use it for a single benefit or for all of them, Nutricog® is a game changer. www.plthealth.com 

---

SD Head USA - Actiserine™

Actiserine™: A New Gold Standard for Brain Health. Shankar Nutricon's Actiserine™ is a clinically proven breakthrough in cognitive support—delivering over 3X the absorption of conventional Phosphatidylserine (PS). This next-generation formula combines PS with catechins and arabinose in a proprietary nanocarrier system, enabling enhanced bioavailability, superior nutrient uptake, and longer-lasting brain benefits. In a double-blind clinical study, Actiserine™ achieved 2.8x higher peak concentration and a 15-hour half-life, all without adverse effects. Whether supporting memory, focus, or healthy aging, Actiserine™ works smarter and harder—raising the bar for cognitive nutrition. It’s not just an improvement—it’s a revolution in brain health. www.shankarnutricon.com 

---

Sempera Organics - SO-DSX1®

SO-DSX1® is a clinically validated organic Lion’s Mane (Hericium erinaceus) blend from Sempera Organics, sustainably produced using proprietary strains and precision mycology. It delivers a full spectrum of bioactive compounds that support cognitive function and mood. In a randomized, placebo-controlled trial published in Nutrients, a single 1.8 g dose improved cognitive reaction time within 60 minutes, with greater cognitive and stress-reduction benefits after 28 days. This is the first known study to show both rapid and sustained effects of lion’s mane in healthy young adults, positioning SO-DSX1® as a powerful ingredient for cognitive health and stress support. www.semperaorganics.com 

---

Stratum Nutrition - SageXtra™

SageXtra™ sage extract is standardized to high levels of rosmarinic acid, the bioactive compound responsible for many of sage’s cognitive benefits. It is 100% traceable and non-GMO, cultivated using specific farming protocols, conditions, and harvesting methods that ensure a consistent and reliable standardized ingredient. Backed by published human clinical trials, sageXtra™ has demonstrated its efficacy. It has been specifically shown to inhibit acetylcholinesterase in vitro, further highlighting its cognitive benefits.* It also offers versatility in consumption, easily integrating into dissolvable powders for both cold and hot drinks, as well as gummies and other innovative delivery formats. www.stratumnutrition.com 

---

TSI - enfinity®

enfinity® is a branded form of paraxanthine, a pure metabolite of caffeine that offers the cognitive benefits of traditional stimulants without common side effects commonly associated with caffeine, like jitteriness, crash, or sleep disruption. Research shows enfinity® supports sustained attention, executive functioning, and mental clarity. As a novel, experiential ingredient, it is ideal for use in cognitive support formulas, nootropic stacks, and energy applications for focus-driven consumers seeking clean, well-tolerated stimulation. www.enfinityenergy.com

---

Digestive Health

Gencor - Trpti™

Trpti™ is an oleoylethanolamide (OAE) ingredient designed to support digestive health, healthy weight management, and metabolic wellness. OEA is a fatty acid ethanolamide produced by the intestine in response to food intake. OEA acts as a signaling molecule that activates PPAR-α, which helps promote lipolysis (the breakdown of fat) and reduces food consumption. Additionally, OEA stimulates the release of GLP-1 through a G protein-coupled receptor-dependent mechanism (GPR119), further aiding in decreasing food intake. These mechanisms collectively contribute to the potential benefits of OEA for a healthy digestive system and microbiome, supporting weight management and metabolic health. www.gencorpacific.com 

---

Groupe Berkem – Biombalance™

Pioneering the next generation of gut health solutions, Groupe Berkem introduces Biombalance™, a science-driven grape seed extract sourced from the prestigious vineyards of Champagne in France. Developed using a proprietary extraction process, Biombalance™ harnesses the power of sustainably harvested Vitis vinifera seeds, offering a unique approach to microbiome support and digestive health. www.groupeberkem.com 

---

Clasado Biosciences - Bimuno® GOS

Targeted gut health support starts with the right functional ingredient. Bimuno® GOS is a clinically proven prebiotic with a low efficacious dose supporting gastrointestinal health from just 1.37g daily. It’s shown to ease bloating, irregularity and discomfort, even in cohorts like those with IBS or following low-FODMAP diets. With fast-acting benefits seen in as little as seven days and excellent tolerability, Bimuno® GOS gives formulators confidence with a research-backed edge. With over 125 scientific publications and 20+ clinical studies, it’s trusted by developers aiming to create digestive health products that meet growing global demands for better gut health. www.clasado.com 

---

COMET – Arrabina® L

Arrabina® L Wheat Fiber Extract is COMET’s newest gut health ingredient. This prebiotic fiber enables formulators to deliver digestive and metabolic health claims without sacrificing products’ taste, functionality or sustainability. COMET’s proprietary Arrabina® line is the only commercially available arabinoxylan-based prebiotic. Arabinoxylan is a well-studied prebiotic fiber with health benefits at a low dose, naturally occuring polyphenols and exceptional tolerability, even at 15 g/day. Arrabina® L is a light-colored fully soluble powder with superior pH and temperature stability, ensuring that it does not break down in extreme manufacturing conditions. Arrabina® L is Upcycled Certified™, NutraStrong™ Prebiotic Verified, FODMAP Friendly, Non-GMO, and Gluten-Free. www.comet-bio.com 

---

Logical Square – CaFi™

CaFi (Cassia fistula) is a brand-new ingredient for the gut health market, which is positioned as a direct competitor to senna products. The biggest difference between CaFi and Cassia angustafolia—the traditional source for senna-based products—is that its sennoside content is low, making it safer for long-term use. Additionally, CaFi works better and faster. In fact, a recent comparison study showed that CaFi outperformed senna in nearly all measures of digestive health. Two more studies are nearing completion for children and seniors, which will further support CaFi’s superiority over senna. CaFi is also highly flexible across many applications. www.logicalsquare.com 

---

Maolac - MaolactinGI

MaolactinGI is a pioneering colostrum-based ingredient, representing a significant advancement in gut health solutions. Developed by Maolac, it utilizes cutting-edge technology and proprietary AI to identify and isolate specific bovine colostrum proteins with remarkable bio-similarity to those found in human breast milk and a proven impact on gut health. This unique combination of carefully selected proteins, delivered at a daily dosage of 330mg, functions by repairing and strengthening the intestinal barrier, addressing micro-inflammation, and creating a favorable environment for beneficial gut bacteria. Its efficacy is supported by a double-blind, randomized, placebo-controlled clinical study, and confirmed by a separate home usage test involving 100 participants. www.maolac.com 

---

Microphyt - ZenGut™

ZenGut™ is a groundbreaking microalgae-based ingredient that revolutionizes holistic wellness through an innovative approach to digestive and mental health. Clinically proven to deliver benefits in just 2 weeks at a low dose of 250 mg/day, it enhances digestive comfort, relieves GI disorders, and supports microbiota balance by increasing microbial diversity—a powerful complement to probiotics. As the world’s first commercial extract of Tetradesmus obliquus Mi175.B1.a, ZenGut™ also supports mental well-being by modulating key neurotransmitters involved in mood and stress—offering a truly unique, fast-acting solution for gut-brain axis health. www.microphyt.eu 

---

NXT USA - Digexin®

This potent herbal dynamo delivers healthy daily regularity in just seven days. It’s not a laxative but a “relaxative.” When you’re stressed, your body shuts down. Working on the gut-brain axis, Digexin® both lowers cortisol and raises serotonin while lubricating the GI tract epithelial lining and hydrating stools for faster, easier transit. Digexin won Ingredient Idol as best-in-class new ingredient at SupplySide West 2023. The International Science & Health Foundation issued a women’s health alert on cortisol gut—stress-induced constipation—which human clinicals show Digexin changes from 3 stools per week (clinical constipation) to once daily, starting in only 7 days. www.nxt-usa.com

---

Microbiome Support

Groupe Berkem – Biombalance™

Pioneering the next generation of gut health solutions, Groupe Berkem introduces Biombalance™, a science-driven grape seed extract sourced from the prestigious vineyards of Champagne in France. Developed using a proprietary extraction process, Biombalance™ harnesses the power of sustainably harvested Vitis vinifera seeds, offering a unique approach to microbiome support and digestive health. www.groupeberkem.com 

---

COMET – Arrabina® L

Arrabina® L Wheat Fiber Extract is COMET’s newest gut health ingredient. This prebiotic fiber enables formulators to deliver digestive and metabolic health claims without sacrificing products’ taste, functionality or sustainability. COMET’s proprietary Arrabina® line is the only commercially available arabinoxylan-based prebiotic. Arabinoxylan is a well-studied prebiotic fiber with health benefits at a low dose, naturally-occuring polyphenols and exceptional tolerability, even at 15 g/day. Arrabina® L is a light-colored fully soluble powder with superior pH and temperature stability, ensuring that it does not break down in extreme manufacturing conditions. Arrabina® L is Upcycled Certified™, NutraStrong™ Prebiotic Verified, FODMAP Friendly, Non-GMO, and Gluten-Free. www.comet-bio.com 

---

Layn Natural Ingredients – Galacan®

Maintaining a healthy microbiome depends on the presence of indigestible polysaccharides that nourish and stimulate the growth of beneficial bacteria and their metabolites. Galacan—a helical exopolysaccharide produced through a patented process—has been shown in several published studies to support the production of short-chain fatty acids and lactobacilli in the microbiome. Derived from a bacterium first discovered in Tibetan topsoil, Galacan stands out for its unique molecular structure, naturally high solubility, and low molecular weight—making it more functional than many conventional prebiotics for use in both food and supplement applications. This marks the first of many innovative ingredients Layn Natural Ingredients will be introducing through its new precision fermentation platform.www.layncorp.com 

---

Nutrileads – Benicaros®

Benicaros® is a clinically validated, low-dose precision prebiotic with a dual mode of action that delivers the same robust, gut health benefits in every type of gut microbiome ecosystem. It also helps to strengthen the immune system. Sourced from upcycled carrot pomace, Benicaros® uniquely supports a resilient gut ecosystem by increasing beneficial bacteria and short-chain fatty acid production with minimal gas production. At just 300mg per day, Benicaros® also trains the innate immune system to respond smarter, faster and stronger. Its formulation friendly properties make it ideal for a broad range of functional food, -beverage, and dietary supplement applications. www.nutrileads.com 

---

Sabinsa – PoZibio®

PoZibio® (heat-inactivated Lactobacillus paracasei D3.5) is a patented, human-origin postbiotic developed by Dr. Hariom Yadav’s team at Wake Forest School of Medicine. Discovered through longevity screening, PoZibio® supports healthy aging by balancing the gut microbiome, enhancing mucin production, sealing the intestinal barrier, and reducing inflammation. It acts as a prebiotic for Akkermansia, promotes metabolic and cognitive health, and improves mood. Preclinical studies show it reduces bloating, gas, and discomfort while strengthening the gut-brain axis. GRAS-certified and U.S.-compliant, PoZibio® is under clinical evaluation in the UK for medical food use and brain health applications. www.pozibio.com 

---

TriNutra - ThymoQuin®

ThymoQuin®, a premium black seed oil standardized to 3% thymoquinone with low free fatty acid content (less than 2%), represents a breakthrough in natural interventions for gut microbiome equilibrium and systemic resilience.
Emerging research highlights its potential to modulate the gut microbiome, promoting beneficial bacteria like Lactobacillus plantarum and Streptococcus thermophilus, while inhibiting harmful pathogens like Klebsiella pneumoniae. In vitro studies demonstrate dose-dependent effects on microbial balance, with clinical evidence suggesting benefits in stress resilience, immune function, and gut-brain-immune support.  This evidence suggests that ThymoQuin® selectively modulates gut bacteria, promoting beneficial strains while inhibiting pathogens, making it a promising candidate for microbiome support. www.trinutra.com

---

Weight Management

FrieslandCampina Ingredients - Excellion® Caseinates

During a weight loss period, consuming sufficient amounts of high quality protein is essential for muscle mass preservation. After the weight loss period, high quality proteins can enhance satiety and prevent over-eating. Our Kosher, Halal, non-GMO and low-lactose Excellion® Caseinates enable you to provide high quality proteins and essential amino acids such as leucine, isoleucine, tryptophan and valine, in a range of formats – from bars to ready to drink shakes. Excellion® Caseinates are spray dried milk proteins, prepared from fresh skimmed milk, used in dietetic, sport and health drinks, medical formulas as well as in (cultured) dairy products. www.frieslandcampinaingredients.com 

---

Gateway Health Alliances - Dyglomera®

Dyglomera® is a patented extract of Dichrostachys glomerata clinically shown to support healthy weight management through multiple metabolic pathways. In more than 10 randomized clinical trials with over 1,000 participants, Dyglomera® has consistently demonstrated significant reductions in body weight, BMI, and body fat. It helps sustain natural GLP-1 activity by inhibiting DPP-4, the enzyme that degrades GLP-1—supporting satiety and appetite control. Dyglomera® also enhances sensitivity to key metabolic hormones including leptin, adiponectin, and insulin. With a low 400-mg daily dose and broad metabolic effects, Dyglomera® offers a safe, natural solution for effective weight management and metabolic health. www.ghainc.com 

---

Maypro - Sirtmax®

Sirtmax® is derived from black ginger (Kaempferia parviflora) and has two primary modes of action. In the first, the polymethoxyflavonoids in Sirtmax upregulate the SIRT1 gene pathway to help protect against mitochondrial decay, thereby supporting energy levels and possibly longevity. In the second, Sirtmax inhibits glycation to support healthy blood sugar levels already within a normal range. These dual modes of action work together to inhibit pancreatic lipase, regulate insulin signaling, provide inflammation modulation, promote a decrease in Advanced Glycation Endproducts (AGEs) and support arterial flexibility.www.maypro.com 

---

Nutraland - Actiz!ng™

Actiz!ng™ is a high-potency black ginger extract (BGE) standardized to 35% polymethoxyflavones (PMF)—the bioactive powerhouses behind its health benefits. In a human clinical trial, Actiz!ng™ demonstrated reductions in visceral fat (i.e., abdominal fat) and waist circumference, while promoting an increase in lean mass and fat-free mass. In addition, Actiz!ng™ also helped improve physical functioning, energy/fatigue, emotional well-being, social functioning, pain, and general health. Growing research on black ginger also shows documented benefits for athletic performance and male sexual health—positioning Actiz!ng™ as a dynamic, natural solution for body composition, vitality, and performance. www.somato.cc 

---

PLT Health Solutions - Slendacor® Weight Management Complex

At PLT Health Solutions, we feel maintaining your weight can be the most important thing you can do to live a long, healthy life. But it’s important we do it right. No gimmicks. No side effects. Slendacor® Weight Management Complex has been shown to help people meet their weight goals rapidly by enhancing lipid metabolism. Its unique ‘mechanism of action’ was demonstrated in a recent clinical study that showed increased resting metabolic rate, thermogenic effects and calorie burning (up to 15% more). The study also showed metabolic health benefits, including lower blood triglycerides and better total and LDL cholesterol. www.plthealth.com 

---

The Protein Brewery - Fermotein®

Neither plant nor animal, Fermotein® by The Protein Brewery is a next-gen mycoprotein born from fermentation—offering a sustainable, nutrient-dense solution for weight management. Made from an IP-protected fungi strain, with fiber and all essential amino acids, Fermotein® delivers complete protein and satiety in one ingredient. Its unique structure supports muscle maintenance while helping curb hunger, making it ideal for better-for-you foods and functional formulas. Produced from fungi and grown without farmland, Fermotein® offers a powerful alternative to traditional proteins—bridging the gap between performance, nutrition, and sustainability. For brands targeting mindful consumers, Fermotein® is the future of nourishment. www.theproteinbrewery.nl 

---

Phynova - Reducose®

Reducose® is finalist for NutraIngredients Award "Botanical Ingredient of 2025". Patented and backed by 11 clinical studies, a single 250-mg dose taken at the start of a meal containing carbohydrates works immediately to reduce post-meal glucose and insulin spikes by up to 40%. Experience better energy and metabolic balance, try Reducose® today. www.phynova.com 

---

TSI - myHMB®

myHMB® (β hydroxy β methylbutyrate) is a clinically validated support for weight management that helps preserve lean muscle while promoting fat metabolism during calorie restriction or time-restricted feeding. Studies show it reduces muscle loss during dieting, enhances fat utilization in muscle cells, and supports reductions in adipose tissue. As weight loss strategies evolve, myHMB® plays a vital role: maintaining strength, metabolic efficiency, and body composition without compromising muscle. Ideal for those prioritizing both fat loss and muscle preservation, it’s a cornerstone ingredient in modern weight management protocols. www.myhmb.com

---

Immune Support

Clasado Biosciences - Bimuno® GOS

Immunity is built, not boosted - and the core foundations are found in the gut. Bimuno® GOS is a prebiotic ingredient clinically shown to support both innate and adaptive immune function by selectively feeding key beneficial bacteria, including bifidobacteria which can influence our immune health. In trials, it’s been shown to increase immunoglobulin A (IgA) levels, reduce pro-inflammatory markers and shorten the duration of respiratory issues. Bimuno® GOS offers real-world immune benefits with flexible application across supplements, functional foods and synbiotics. For brands developing immune support products grounded in science, Bimuno® GOS shows the future of targeted nutrition. www.clasado.com 

---

Lycored - Lycomato⁶™

Lycomato⁶™ is Lycored’s flagship health extract made from a proprietary breed of red tomatoes, containing optimal concentrations of lycopene, phytoene, phytofluene, phytosterols, tocopherols, beta-carotene, and essential vitamins. Lycomato⁶ supports immunity through antioxidant activity, anti-inflammatory properties and enhancement of T-cell function. Lycomato⁶ helps protect immune cells from free radicals, reduces inflammation and offers a boost in natural cell support to help the body detox. By helping optimize the immune system, Lycomato⁶ enables normal saturation in the body and promotes nutrient delivery to all tissues. Lycomato⁶ significantly impacts the mitochondria, minimizing dysfunction and cellular senescence, slowing cellular aging and supporting longevity.www.lycored.com 

---

Nutrileads – Benicaros®

Benicaros® is an upcycled precision prebiotic clinically shown to train the innate immune system to respond faster, smarter and stronger. In a randomized, placebo-controlled trial with 146 healthy adults, daily supplementation (300 mg) for 8 weeks significantly reduced common cold symptom severity (20–33%) and duration (28–43%) following a rhinovirus challenge. Quality-of-life disruptions dropped by 10–30%. Benicaros® enhanced critical immune defenses—interferon signaling, innate immune cell activity, and natural killer cell responsiveness—only when needed, without overstimulation. Benicaros® also consistently increases beneficial gut microorganisms and is formulation friendly, making it suitable for functional foods, beverages, and dietary supplements. www.nutrileads.com 

---

PLT Health Solutions - Spectramune® Immune Defense Complex

How many supplements or ingredients are you using right now to improve your immune system? What if it could be just one? Spectramune® Immune Defense Complex is a synergistic combination of ashwagandha and Haritaki that provides a broad range of immune health benefits, including reduced incidence of illness, improvements in a range of immune biomarkers and an overall improvement in psychological wellbeing. Unlike other immune health ingredients, Spectramune targets both innate and adaptive immune responses for broader protection. Studies have shown that people using Spectramune get sick less often and have less severe symptoms when they do get sick. www.plthealth.com 

---

Toei Shinyaku - King Agaricus 21

King Agaricus 21 is the only outdoor-cultivated Agaricus blazei in the world which grows in the wild without any pesticides or GMO technology. All the other Agaricus are indoor cultivated. Our cultivation method makes it considered very safe in the U.S., Europe, and Asia. It is bigger, has higher nutrition value, and demonstrates better efficacy than other Agaricus. It mainly contains beta-glucan, vitamin D, and Calcium, but also many other vitamins, minerals, amino acids, and other bioactive nutrients. Such complex nutrient combinations provide consumers with multiple health benefits like immunity, hair growth, anti-infection, menopause etc. for both women and men. www.agaricus.co.jp

---

Women’s Health

Applied Food Sciences - CelluThrive™ D-Glucarate

CelluThrive™ is a powerful ingredient that enhances cellular health and wellness. Rooted in over two decades of science, CelluThrive™ has been clinically shown to support many key health states today, including hormone balance for healthy aging in women. Hormone fluctuations are a natural part of aging. However, when estrogen levels become unbalanced, especially during perimenopause and menopause, it can disrupt energy, mood, and sleep. While many products look to address these symptoms individually, CelluThrive™ works at the root of the problem, helping women remove excess estrogen and xenoestrogens (estrogen mimickers) to restore hormonal balance in the body. www.appliedfoods.com 

---

Ennature Biopharma - Gingeren®

Gingeren® is an ultra-low dose ingredient standardized to 20% total gingerols, developed using sustained release technology for enhanced half-life by 5x along with enhanced overall tolerability. The sustained release profile of the bio-actives (gingerols) makes the ingredient suitable to address broad health indications, both acute (nausea and dyspepsia) and chronic (weight management, dysmenorrhea and female sexual wellness). Gingeren® is clinically studied to improve the general health of menstruating women, promoting an active lifestyle. www.ennaturebiopharma.com 

---

Ethical Naturals - Cranberex®

In 1998 studies published by Amy Howell et al confirmed that the A-Type proanthocyanidins (PAC's) unique to cranberry are responsible for their Urinary Tract Health (UTH) benefits by preventing bacteria from adhering to the urinary tract through their Anti-Adhesion Activity (AAA).
Cranberex® is standardized for active, therapeutic levels of these A-Type PACs. Its powerful AAA has been demonstrated in two clinical studies at Rutgers University by Amy Howell. Now, when urinary tract infections cause about 10.5 million doctor office visits each year, scientifically supported approaches to UTH from natural sources are of growing value. Cranberex® fulfills this important role. www.ethicalnaturals.com 

---

GC Rieber - VivoMega® Algal Oil

VivoMega® Algal Oil delivers high-potency, plant-based omega-3s (DHA+EPA) with exceptional purity, quality, sustainability, taste, and smell. Backed by published clinical research, algal omega-3s have been shown to significantly support pre and postnatal health for the baby and mother, as well as brain, cognition, and mood support, heart health, and eye health—key concerns throughout every stage of a woman’s life. VivoMega’s commitment to sustainability and quality ensures a potent, sensory-pleasing omega-3 alternative. With superior bioavailability and a neutral taste profile, VivoMega® Algal Oils meets the growing demand for effective, vegan-friendly solutions tailored to women's specific health needs. www.vivomega.com 

---

Gencor - Libifem®

Libifem® is a patented, standardized fenugreek extract that has been clinically proven to significantly enhance women’s sports and exercise performance, as well as body composition. The first-of-its-kind gold-standard clinical study involving an all-female athlete group showed notable increases in muscle strength and endurance, body composition, leg power, muscle recovery, and pathological markers. Additionally, Libifem has been shown to raise estradiol levels to help alleviate menopausal symptoms, boost sexual health, and improve quality of life during menopause. www.gencorpacific.com 

---

Graminex - PollenBerry®

PollenBerry® is a powder blend of Graminex® G60® and Cranberry Powder for applications in urinary tract health and urinary incontinence. It is clinically supported to significantly reduce stress-induced urinary leakage in women. Available as a powdered ingredient and in solid dose formats. Made in the USA. www.graminex.com 

---

Kaneka - Ubiquinol®

Oxidative stress can affect reproductive health, menopausal health, cardiovascular health, and healthy aging in women. Kaneka Ubiquinol® is bioidentical to the body’s natural ubiquinol and is the active antioxidant form of CoQ10. Its lipid solubility allows ubiquinol to penetrate mitochondrial membranes, supporting the generation of ATP and helping to fight oxidative stress. Kaneka Ubiquinol® can:
• Support healthy mitochondrial function essential for the health of the egg and oocyte.
• Decrease irritability, sensitivity, stress, and mood swings in post-menopausal women.
• Support vessel health and protect LDL cholesterol from oxidation.
• Increase plasma ubiquinol levels, which is associated with cardiovascular health, muscle health, and physical functioning in older adults. www.kanekanutrients.com 

---

KSM-66 - Ashwagandha®

KSM-66 Ashwagandha® is the most clinically studied Ashwagandha with 50+ trials and featured in over 4500 products in over 65 countries making it the largest natural product ingredient brand in the world. KSM-66 has been evaluated in 10+ randomized, double-blind, placebo-controlled trials on women’s health. In seven clinical studies, KSM-66 was shown to improve arousal, lubrication, orgasm, and satisfaction, while also significantly reducing Female Sexual Distress Scale scores and increasing sexual encounters. Additionally, in three studies involving perimenopausal and menopausal women, KSM-66 significantly reduced MRS and MENQOL scores, hot flash frequency, and stress levels, while increasing serum estradiol and enhancing quality of life. www.ksm66ashwagandhaa.com 

---

Lycored - Lycomato⁶™

Lycomato⁶™ is Lycored’s flagship health extract made from a proprietary breed of red tomatoes, containing optimal concentrations of lycopene, phytoene, phytofluene, phytosterols, tocopherols, beta-carotene, and essential vitamins. Lycomato⁶ shows beneficial results in postmenopausal women, supporting healthy aging and longevity through hormonal balance. Its antioxidant properties contribute to bone health in women by activating signaling pathways that play a crucial role in bone formation. Tissue-specific estrogenic activity of lycopene, one of the primary antioxidants in Lycomato⁶, can enhance estrogenic activity in bone cells where it is needed while balancing estrogenic activity in the breast where it is a risk factor. www.lycored.com 

---

NXT USA - Xeya™ Modern Shatavari

Shatavari is lauded as “herb of the year for 2025.” Xeya™ Modern Shatavari is standardized to 15% shatavarins, making for a market-leading small effective dose of only 50-100 mg (compared to 500 mg). Xeya boasts two human clinicals showing balanced hormones in women, specifically on younger women with PCOS, resulting in healthier ovaries, clearer skin, metabolic support, and on older women in perimenopause with fewer hot flashes and night sweats, improved mental clarity, better mood, stress resilience and sleep. Shatavari is revered in Ayurveda as “Queen of Herbs,” and is poised to take its place next to the king (ashwagandha). www.nxt-usa.com 

---

ProBiotix Health - YourBiotixMH

The decline in oestrogen during menopause affects heart health, bone density, mood, and energy. YourBiotixMH by ProBiotix Health is a science-backed, multifunctional formulation that addresses these challenges during and after menopause. Powered by LPLDL®—a patented probiotic clinically proven to lower LDL cholesterol and blood pressure—it also includes Isoflavones, B vitamins, and vitamin D to support hormonal balance, bone strength, and psychological well-being. With LPLDL® shown to enhance vitamin D uptake, YourBiotixMH offers clinically validated, natural support that goes beyond hot flushes, setting a new benchmark in women’s health supplementation. www.probiotixhealth.com 

---

Probi - Women’s Health by Probi®

Women’s Health by Probi® – Iron Absorption pairs the extensively studied LP299V® probiotic strain with iron to support faster and more efficient iron uptake. Multiple clinical trials demonstrate that this combination enhances iron absorption and helps restore iron stores more effectively than iron alone—while also reducing the gastrointestinal side effects common with iron supplementation. With iron deficiency impacting over one-third of women globally, this concept delivers a scientifically substantiated solution to a critical health concern. Designed for ready formulation across dosage formats, Probi’s iron absorption concept brings meaningful innovation and strong clinical backing to the women’s health category. www.probi.com 

---

Puredia - Omegia®

Omegia™: Clinically Proven, Non-Estrogen Menopause Relief Formula
Puredia’s Omegia™, a clinically proven vegan omega-7 formula derived from sustainably harvested organic sea buckthorn berries grown on our pristine Tibetan Plateau farm. Enriched with omega fatty acids (3, 6, 7, and 9), beta-carotene, vitamin E, and plant sterols, uniquely stimulates mucous membrane regeneration throughout the body. Omegia™ as the natural and organic solution to women’s health. Study found it improves vaginal lining integrity by 50%, increases vaginal hydration and elasticity by 33%, enhances skin hydration by 49%, reduces wrinkles by 14%, and relieves dry eyes and mouth. www.puredia.com 

---

Sabinsa – Sabeet®

Sabeet® is a standardized beetroot extract (Beta vulgaris) containing 2% dietary nitrates, clinically shown to support cardiovascular health and exercise performance. A groundbreaking 2025 study found that 12 weeks of nitrate-rich Sabeet® significantly improved carotid artery stiffness in postmenopausal women—an at-risk group for cardiovascular disease—without altering blood pressure. By boosting nitric oxide (NO) levels, Sabeet® enhances blood flow, vascular function, and arterial compliance. It also improves endurance, reduces exercise-induced muscle damage (LDH), and lowers inflammation markers (CRP, ESR). Sabeet® offers a science-backed, non-pharmacological strategy for improving vascular health, athletic performance, and healthy aging, particularly in postmenopausal women. www.sabinsa.com 

---

Seipel Group - Urox®

51 million American women suffer incontinence, postpartum to post menopause, with urgency, frequency and waking repeatedly “to go” at night, relying on adult diapers/pads. Urox®, a patented, three-herb blend backed by 20 years of research, 14 clinical trials and a mechanism of action study is shown to support women’s health, strengthening bladder tone and compliance, pelvic floor muscles, and calming bladder nerves in 2 – 8 weeks. Effective for 90% users, Urox® reduced incontinence by 65% and diaper/pad use by 75%, with improved sleep, lowered anxiety and greater social wellbeing. Urox® empowers women, increasing confidence and control at every life stage. www.seipelgroup.com 

---

TSI - OptiCreatine™

OptiCreatine™ is a breakthrough creatine processing platform that enhances solubility, improves tablet compactness, and expands creatine applications into formats such as chewables, providing greater flexibility across formulations. With growing awareness of creatine’s role in supporting strength, energy metabolism, and cognitive performance, OptiCreatine™ offers a modern solution tailored for women’s health products. It enables clean, clear, and easy-to-use formats that address common concerns like grittiness or consumer experience, helping brands deliver creatine in more approachable ways for female consumers. www.tsigroupltd.com 

---

Vegan Minerals – WholeCal™

WholeCal™ is a whole-food calcium ingredient derived from clinically supported red marine algae, offering bioavailable calcium, magnesium, and 70+ naturally occurring trace minerals and amino acids. While most traditional calcium supplements are made from rocks or synthetics that the body struggles to absorb, WholeCal™ delivers calcium in a natural matrix the body can readily utilize. This is critical for maintaining bone strength and mobility, particularly for women, who face an increased risk of bone loss with age. Sustainably harvested and minimally processed, this premium solution is essential for women’s wellness and ideal for supplements, functional foods, and beverages. www.veganminerals.com

---

Men’s Health

Gencor - Tesnor®

Tesnor® is a proprietary blend of two herbal extracts: cocoa bean (Theobroma cacao) and pomegranate peel (Punica granatum). It has been clinically proven to boost muscle strength and growth in young males, while another study shows that it significantly alleviates age-related symptoms in men. Daily doses of Tesnor® have been shown to increase testosterone levels and reduce Aging Male Symptoms Scores. At just 200 mg per day, Tesnor provides both young and aging men with significant support as a natural testosterone booster. www.gencorpacific.com 

---

Graminex - G63®

G63® Flower Pollen Extract is our flagship product in men’s health and has been recently added to the American Urological Association Guidelines for chronic pelvic pain. It is clinically supported for BPH, CPPS and abacterial chronic prostatitis. It is a blend of both lipid and water-soluble extracts of pollen, standardized to specific levels of amino acids and phytosterols. Made in the USA. www.graminex.com 

---

KSM-66 - Ashwagandha®

Known in Ayurvedic medicine as “King of Herbs”, Ashwagandha root and in particular KSM-66 is currently one of the most sought out and most clinically proven botanical in the world for Men’s Health. KSM-66 has been evaluated in over 8 clinical trials for men’s health and was found to be effective in improving sperm count, sperm motility, semen volume, testosterone, libido, sexual desire, sexual function, and satisfaction. In stressed men, KSM-66 also reduced cortisol levels. Backed by 46+ global quality certifications, KSM-66 is one of the most widely used botanical ingredients in hundreds of men’s health products worldwide. www.ksm66ashwagandhaa.com 

---

Lycored - Lycomato⁶™

Lycomato⁶™, Lycored’s flagship health extract made from a proprietary breed of red tomatoes, contains optimal concentrations of lycopene, phytoene, phytofluene, phytosterols, tocopherols, beta-carotene, and essential vitamins. Lycomato⁶ may benefit prostate health and comfort, as its antioxidant properties help combat oxidative stress and reduce inflammation, lowering the risk of prostate-related symptoms. Studies show high levels of lycopene from supplementation can slow prostate cell growth, which has a beneficial effect on prostate gland volume and prostate-specific antigen (PSA) levels, a primary marker for prostate cancer. Lycomato⁶ is shown to protect against cellular damage to slow cellular aging and support longevity. www.lycored.com 

---

Nutrition21 - Nitrosigine®

Nitrosigine® is the superior nitric oxide booster delivering a unique bioavailable form of arginine, which the body uses to make nitric oxide. Nitric oxide is an important part of healthy sexual function and vitality but naturally declines with age. By promoting nitric oxide production, Nitrosigine promotes healthy blood flow which can help support men’s sexual performance, healthy arousal, and satisfaction. Nitrosigine’s clinically backed efficacy and rapid action are supported by over 30 studies, including 8 clinical trials, and can be formulated into a range of men’s healthy lifestyle products, including tablets, capsules, powders, beverages, and bars. www.nutrition21.com 

---

PLT Health Solutions - TestFACTOR® Sexual Wellness & Longevity

Is it OK to talk about supplements for men’s sexual well-being? We think it is, but only if we have the clinical studies to back up what we say. TestFACTOR® Sexual Wellness & Longevity is backed four clinical studies demonstrating that TestFACTOR is as good or better than any botanical in supporting increased testosterone – helping young men get bigger and stronger and older men be more vital. The most recent TestFACTOR clinical showed improvements in overall sexual function, sexual frequency, sexual satisfaction and erections (yes, we went there). TestFACTOR can power products that any will interest any man. www.plthealth.com 

---

Seipel Group - Urox®

Male bladder problems are often mistaken for prostate issues — but almost half the time the real cause is overactive bladder, with rigid, yet overstimulated, bladder muscles that don’t relax and properly fill, nor fully contract and completely empty. Urox® patented herbal formula delivers urinary results where men need them most: calming and supporting bladder muscle compliance for a stronger stream with more volume, reducing urgency, frequency and halving nighttime bathroom trips. Urox® reduces bladder accidents by 57%, restoring bladder confidence and sleep quality. Urox®, a proven, targeted bladder solution reduces disruptions, helping men stay strong, energized, active and in control. www.seipelgroup.com 

---

TSI - myHMB®

myHMB® supports muscle mass, strength, and recovery—factors critical for men pursuing active aging, performance, or body composition goals. By reducing muscle protein breakdown and supporting muscle protein synthesis, myHMB® helps men retain physical function as they age or pursue training outcomes. Its synergies when paired with protein, creatine, or vitamin D, offering targeted support for muscle health in sports nutrition and men’s wellness formulas. www.myhmb.com

---

Nutri-Beauty

Activ'Inside - Belight³™

Belight³™ is a patented oral nutricosmetic solution designed to reduce age- and sun-related hyperpigmentation and dark spots, promoting a more even skin tone. Its synergistic blend of grape seed extract, licorice extract, grape pomace extract, and coated vitamin C targets melanin production at the source by inhibiting tyrosinase activity by 85%. Clinically validated through two gold-standard studies—first on Asian skin and later on Caucasian skin, Belight³™ boasts high consumer satisfaction, reinforcing its strong competitive edge in the rapidly expanding beauty and wellness market.www.activinside.com 

---

FrieslandCampina Ingredients - Biotis® Lactoferrin

Biotis® Lactoferrin is the optimal solution for natural protection from within. As one of the world’s most consistently high quality lactoferrin ingredients, it delivers science-backed results across several consumer health categories, from immune, skin and bone health, to sports nutrition, healthy aging and women’s well-being. Informed by over 25 years of expertise, our sophisticated spray-drying technology results in an ingredient with narrow particle size distribution for optimal blending, homogenizing and tableting properties. The highest quality fresh milk, carefully sourced from our member farms, is processed via our specially designed mild heat-treatment, guaranteeing a lactoferrin product with 95% purity at minimum. www.biotis.com 

---

Gnosis by Lesaffre - Emothion®

Emothion® is a unique crystalline S-acetyl-glutathione (SAG) form patented by Gnosis by Lesaffre. Unlike conventional glutathione, it offers superior cellular uptake and antioxidative properties, maximizing the inner oxidative stress balance.
Emothion® has a faster dissolution rate and more efficient absorption, making it more effective for oral intake. As a potent antioxidant, Emothion® can benefit skin, brain, and liver health. www.gnosisbylesaffre.com 

---

Lycored - Lumenato™

Lumenato™ is a standardized yellow tomato extract exclusively by Lycored. Derived from a proprietary breed of yellow tomato, Lumenato’s active components—phytoene and phytofluene—are colorless carotenoids scarcely found in nature. These compounds have a unique capacity to protect the skin from UVB radiation. Lumenato works from the inside out to build a reservoir of goodness that supports building blocks of skin health, repair and recuperation. Backed by four pre-clinical trials and three clinical trials, Lumenato is shown to support skin structure, boosting and protecting collagen and influencing ceramides for improved skin barrier function, hydration, elasticity, firmness and radiant glow. www.lycored.com 

---

Maypro - Mesoporosil®

Mesoporosil® is an innovative source of bioavailable silicon, addressing the limitations of conventional silicon ingredients. Although silicon is the second most abundant mineral on Earth, it is often overlooked despite its crucial role in maintaining the structure of bones, joints, and skin. It is an essential co-factor for collagen production and supports bone mineralization by stimulating osteoblast activity. While various silicon sources exist in the ingredient industry, most are poorly bioavailable, as they polymerize into an insoluble form upon passing through the gastric environment. Mesoporosil® solves this problem through a patented manufacturing process, ensuring silicon remains in a soluble monomeric form upon reaching the intestines, making absorption through the mucosal lining possible. www.maypro.com 

---

Mibelle AG Biochemistry - PhytoCellTec™ Md Nu

PhytoCellTec™ Md Nu is an innovative ingredient that revitalizes skin stem cells using advanced, sustainable plant cell culture technology. Derived from the rare Swiss apple variety Uttwiler Spätlauber, it is rich in epigenetic factors helping to boost skin vitality. Backed by a published clinical study, just 10 mg PhytoCellTec™ Md Nu daily significantly improves skin firmness, elasticity, and density with participants reporting smoother skin and a strong desire to continue use post-study. Offering scientifically backed anti-aging benefits, PhytoCellTec™ Md Nu is an ideal nutricosmetic ingredient for beauty-from-within and skin rejuvenation supplements. www.mibellebiochemistry.com 

---

Nutrition21 - Lustriva®

Lustriva® is a patented, one-of-a-kind blend of Bonded Arginine Silicate and Magnesium Biotinate delivering unique and bioavailable forms of silicon and biotin that work together to promote healthier looking hair and skin. Lustriva® is clinically shown to support existing hair growth in as few as three weeks, providing a fuller and thicker look while improving the appearance of skin within twelve weeks. By promoting the nutritional and structural support for hair and skin, Lustriva® is a safe and effective way to look your best from the inside out and is easily formulated into tablets, capsules, powders, beverages, and bars. www.nutrition21.com 

---

Sabinsa – Babchiol™

Babchiol™ is a botanical extract delivering 99% pure Bakuchiol from Psoralea corylifolia, a natural alternative to retinol without the irritation. Clinically shown to visibly reduce fine lines, improve skin texture, restore firmness, and enhance radiance, Babchiol™ also inhibits collagenase and elastase—enzymes that break down skin structure. Unlike retinol, it offers superior UV protection, no phototoxicity, and is safe for all skin types. With proven antioxidant and anti-aging benefits, Babchiol™ defends against environmental damage and premature aging. Gentle yet powerful, Babchiol™ is where advanced science meets natural renewal, offering retinol-like results with unmatched skin compatibility and long-term protection. www.sabinsa.com 

---

Stratum Nutrition - OVOLUX™

OVOLUX™ is a powerhouse beauty ingredient clinically shown to help reduce the visible signs of skin aging, including fine lines and wrinkles, giving you a smoother, more youthful complexion. Naturally occurring bioactive nutrients in OVOLUX™ help improve hair strength and texture, as well as promoting stronger, healthier nails. In 12 weeks, OVOLUX™ produces visible improvements in hair and skin texture. And, in just 6 weeks, OVOLUX™ significantly improves skin hydration, firmness and elasticity, particularly around the delicate eye area, helping reduce the appearance of crow’s feet and fine lines.* www.stratumnutrition.com 

---

VeCollal® Type 1– Plant-Based Beauty That Works

VeCollal® is a breakthrough in nutri-beauty: a 100% plant-based collagen alternative that mirrors human collagen with precision. Clinically shown to reduce wrinkles by 33% in just 8 weeks, it’s the perfect choice for brands looking to deliver real results—naturally. VeCollal® supports smoother, firmer, more radiant skin from within, using a blend of fermented amino acids, vitamin C, and essential co-factors. Clean, sustainable, and vegan-friendly, VeCollal® offers the power of collagen—without the animal. www.vecollal.eu

---

Delivery Systems

Akay Bioactives - FenuMat®

FenuMat® is a clean-label delivery technology that effectively enhances the bioavailability, stability, and organoleptic properties of bioactive nutrients. Utilizing fenugreek fiber, FenuMat forms a plant-based protective hydrogel around bioactive compounds, improving their solubility and enabling controlled release for better absorption. Ideal for vitamins, oils, and other actives, FenuMat supports co-delivery for enhanced efficacy and lower dosages. It can also be seamlessly integrated into powders, gummies, sachets, and more—meeting the demand for clean label formulations, without organic solvents or synthetic excipients.www.akaybioactives.com 

---

Maypro - Sucrosomial® Magnesium

Sucrosome® Technology is an advanced nutrient delivery system designed to protect and enhance absorption of essential micronutrients. In the U.S., it is best known for Sucrosomial® Magnesium, which encapsulates magnesium oxide in a phospholipid bilayer with sucrose esters of fatty acids. Beyond absorption, Sucrosome® Technology offers additional benefits. It reduces gastrointestinal discomfort, minimizing side effects like nausea. It also eliminates the metallic taste often associated with magnesium oxide, improving overall tolerability. In summary, this innovative approach optimizes nutrient absorption, tolerability, and taste, making it a more effective and user-friendly supplement option. www.maypro.com 

---

Maypro - MicroActive® Melatonin

Melatonin is a key hormone that regulates the circadian rhythm, helping the body respond to the absence of light and prepare for sleep. For individuals struggling with sleep due to lifestyle factors or disruptions in their natural sleep cycle, melatonin supplementation can be beneficial. However, melatonin has a short half-life in the body, which means its effects may diminish too quickly, potentially leading to difficulties in staying asleep throughout the night. To overcome this limitation, MicroActive® Melatonin was developed using MicroActive® technology, a specialized delivery system designed to enhance absorption and provide sustained release. www.maypro.com

---

Plant-Based

Gencor - 4Liver®

Meet the intersection of ancient Ayurveda wisdom and Gencor’s advanced science with 4’Liver. 4Liver is a powerful herbal extract that combines two Ayurvedic botanicals: Terminalia chebula (fruit) and Sphaeranthus indicus (flower). T. chebula and S. indicus are adaptogenic herbs; adaptogens help the body manage physical, chemical, or biological stress. 4Liver is clinically proven to support liver health, improve lipid profiles, and boost antioxidant levels. www.gencorpacific.com 

---

GC Rieber - VivoMega® Algal Oil

VivoMega® Algal Oil sets a new standard in plant-based omega-3 innovation. Derived from microalgae, it provides a highly potent, sustainable source of EPA and DHA to meet evolving consumer demands for clean, ethical, and effective nutrition. Produced using the proprietary SuperLight™ process, VivoMega® ensures exceptional oxidation protection and minimal heat exposure, delivering market-leading purity and stability. With zero waste, optimal raw material utilization, and formats including pure DHA or EPA+DHA, VivoMega’s certified vegan, non-GMO, and Halal Algal Oils are the future of high-performance, plant-based omega-3 solutions.www.vivomega.com 

---

Ingredients by Nature - Eriomin®

Glucagon-like peptide 1 (GLP-1) is drawing attention from researchers due to its association with multiple health benefits. This naturally occurring hormone helps manage healthy blood glucose levels, supports brain health, cardiovascular health, and may aid in healthy weight management. Eriomin® is a plant-based, lemon flavonoid blend clinically backed by three published human trials to naturally increase endogenous GLP-1 levels. Eriomin’s research further demonstrates sustained GLP-1 levels compared to transient levels. www.ingredientsbynature.com 

---

Natures Crops International - Ahiflower®

Grown regeneratively in the UK, Ahiflower® is nature’s richest source of omega-3 offering the most complete and balanced omega 3-6-9 profile. With superior EPA conversion and efficient whole-body DHA enrichment compared to flax plus a clean, mild taste, Ahiflower® delivers powerful support for brain, heart, gut, joint, immune, and skin & hair health—without the taste or environmental impacts of fish oil. Sustainably cultivated and fully traceable, Ahiflower® meets growing consumer demand for clean, effective, and planet-friendly omega-3 nutritional benefits. It’s the natural choice for brands looking to lead in plant-based innovation and integrity. www.ahiflower.com 

---

Nutralliance - Ravetol 30P®

Ravetol 30P® is a natural mixed tocopherol that is an excellent alternative to traditional soy derived tocopherols. Produced from European rapeseed oil, the Ravetol 30P® is Project Non-GMO Verified and allergen free. It provides natural antioxidant protection from rancidity in foods containing fat, cosmetic and personal care products, nutritional bars and powdered drink mixes and even pet food. It has very good solubility in oils and fats, is Kosher and Halal Certified and tested by a 3rd party lab on every batch. Ravetol 30P® boasts a minimum of 30% tocopherols with a high alpha content, making it a great source of vitamin e. www.nutralliance.com 

---

Nutralliance - Sunvitol® E500

Sunvitol® E500 is a natural Vitamin E powder derived from sunflower. Because sunflower oil contains primarily d-alpha tocopherol, chemical modification of the molecule is not necessary for extraction. This makes it the most natural form of vitamin e available. Highlights include Non-GMO Project Verification, clean label, silica free, kosher and halal certified and 3rd party testing for every lot. Sunvitol® E500 is produced in the USA and can be incorporated into a number of applications, including powdered drink mixes, capsules, tablets, gummies, bars and so many others. With 24-month shelf stability, it delivers 336 mg/g d-alpha tocopherol. Sunvitol® E500 is unique and high in demand. www.nutralliance.com 

---

Nutrileads – Benicaros®

Benicaros® is a science-backed, plant-based precision prebiotic and immune-training fiber upcycled from carrot pomace—one of the world’s most trusted vegetables. This clinically validated rhamnogalacturonan-I (RG-I) fiber delivers dual-action benefits: it trains the innate immune system to respond smarter, faster, and stronger and supports a resilient gut microbiome in all gut ecosystems. Benicaros® is traceable from farm to finished product and with a daily serving size of as low as 300 mg, Benicaros® offers sustainable, multifunctional health support—enabling functional food, -beverage, and dietary supplement brands to meet consumer demand for clean-label, upcycled, and planet-friendly innovation. www.nutrileads.com 

---

Sloiron, Inc - SloIron®

SloIron® is the only ferritin-iron complex from legumes on the market. SloIron® is a plant-based, non-irritating, bioavailable, vegan source of iron. SloIron® is innovative because it has a dedicated absorption mechanism unlike any other iron form that allows the ferritin protein cage that surrounds the Fe at the core to stay completely intact when absorbed into the gut. This means the reactive Fe is never exposed to the gut cell wall, protecting it from gastrointestinal discomfort side effects of other iron supplements. Ferritin-iron has a slow-release mechanism that allows the iron to be utilized only when the body needs it. www.sloiron.com 

---

The Protein Brewery - Fermotein®

Not a plant—but redefining plant-based. Made from an IP-protected strain, Fermotein® is a whole-food, fungi-based mycoprotein made through fermentation. Rich in fiber and complete protein, it delivers balanced nutrition that supports energy, fullness, and metabolic health—without the footprint of traditional crops. Grown using minimal land, water, and resources, Fermotein® offers food and beverage brands a highly sustainable, clean-label ingredient for next-gen plant-based innovation. With its neutral taste, versatile functionality, and nutrient density, Fermotein® empowers formulators to meet the growing demand for whole, satisfying, and environmentally smart protein solutions - no compromise, no animals, and no ordinary plants required. www.theproteinbrewery.nl 

---

VeCollal® – Plant-Based with a Purpose

VeCollal® is a next-generation, plant-based collagen alternative that delivers real beauty results—without the environmental cost. Swapping just 1 kg of bovine collagen for VeCollal® saves as much CO₂ as 1.7 trees absorb in an entire year. Clinically proven to reduce wrinkles by 33% in 8 weeks, VeCollal® offers the same amino acid profile as human collagen, but made entirely from fermented, vegan ingredients. Clean, sustainable, and animal-free, it’s perfect for beauty-from-within and joint health products that align with conscious consumer values. Better for you. Better for the planet. www.vecollal.eu

*THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT, CURE OR PREVENT ANY DISEASE.

Individuals who complete the full ballot, selecting their choice in every category, can be entered to have a $100 donation to Vitamin Angels made in their name. Complete the form with your name and email address to be in the pool for selection. Winner will be selected at random. If you want to be eligible, please provide your name and email using the form below.