The Council for Responsible Nutrition (CRN) has submitted a Citizen Petition to the U.S. Food and Drug Administration (FDA) calling for the agency to reconsider its interpretation of the Drug Preclusion Clause. 

In November 2022, a notification by the Food and Drug Administration (FDA) declared that beta-nicotinamide mononucleotide (NMN) is not a legal dietary ingredient. In response, the Natural Products Association (NPA), along with the Alliance for Natural Health (ANH), submitted a Citizen’s Petition to FDA. 

Following the November 2022 notification by the Food and Drug Administration (FDA) that beta-nicotinamide mononucleotide (NMN) is not a legal dietary ingredient, Amazon’s Restricted Products Team emailed sellers in February that products containing NMN would be banned after March 13, 2023.