Bradenton, FL—A new study has been published inPhytotheraphy Research showing thatParActin, a patented extract ofAndrographis paniculate, confers benefits in those with knee joint discomfort, according to a press release from HP Ingredients.

The study examined the efficacy of doses of 300 and 600 mg of ParActin or placebo daily for 84 days in 103 adults with mild to moderate osteoarthritis of the knee. The result: There was a significant and progressive reduction in pain score in both ParActin groups starting at day 28 compared to placebo. ParActin subjects showed “highly significant” improvements in physical function score, bodily pain score,\ and social function score. Markers of fatigue also improved.

Researchers in the present study concluded, according to the press release: “We propose that ParActin can decrease the pain and discomfort of knee osteoarthritis and improve the patient’s general condition and quality of daily life, with no major adverse events.”

Annie Eng, CEO of HP Ingredients, added: “ParActin has a solid body of evidence showing its ability to regulate a healthy inflammatory response, and high inflammation is a key characteristic of knee discomfort. This study shows ParActin has value for keeping people moving and active with less restriction.”

This study adds to the growing body of research showing ParActin’s efficacy in supporting joint health, according to the release. Previous studies have shown that Andrographolide inhibited cartilage matrix-degrading enzymes, and increases antioxidant enzyme activity.