Continue To Site >
Quicklinks
  • Ask Whole Foods Mag
  • Magazine Subscription
  • View Back Issues
  • Advertise
  • Education Center
  • Ashwagandha / Shatavari Experience
  • Naturally Informed
  • Move Nutrition
  • India-America Boardroom Series
Free Newsletter Subscription
Ask WholeFoods Mag
  • News
    • All News
    • In Case You Missed It
    • Breaking News
    • Grocery News
    • Dietary Supplements News
    • Supplier News
    • Health & Beauty Aid News
    • Green News
    • Research
  • Features
    • Supplements
    • Grocery
    • Health & Beauty Aids
    • Suppliers
  • Columns
    • Debates
    • Editorial
    • Good Health Reads
    • Happy Customer
    • Herb of the Month
    • Leadership Profiles
    • Legal Tips
    • Mentors
    • Merchandising Insights
    • Recipes
    • Naturally Informed Education
    • The Nutrition Mythbuster
    • Trade Secrets
    • Vitamin Connection
    • What's Selling
    • WholeFoods Blogs
  • Products
    • Dietary Supplements
    • Grocery Products
    • Gourmet Products
    • Health & Beauty Aid Products
    • New Product Reviews
      • 2021 Archives
      • 2019 Archives
      • 2018 Archives
    • Suppliers
  • Multimedia
    • Videos
    • Podcast
    • The Natural View
  • Directory
Ask WholeFoods Mag
  • Log In
  • Register
  • Log Out
  • My Account
Free Newsletter Subscription
Quicklinks
  • Ask Whole Foods Mag
  • Magazine Subscription
  • View Back Issues
  • Advertise
  • Education Center
  • Ashwagandha / Shatavari Experience
  • Naturally Informed
  • Move Nutrition
  • India-America Boardroom Series
Home » SPONSORED BY

Nootropic for Optimizing Overall Cognitive Health

Nootropic (2).jpeg
September 19, 2022
Danielle Citrolo, PharmD and WholeFoods Magazine Contributor
This time of year, many people are seeking something to help them maintain or improve their mental energy, memory, focus, and attention to get the day-to-day things done, let alone get ahead during a changing environment. The need for mental stamina is even more demanding. This is true, no matter the activity.

A certain amount of physical activity enhances mental function, but as it becomes more intense, it places a higher demand on the brain. Unlike muscles, the brain does not store energy. The brain needs a consistent form of nourishment to continually generate the mental acuity it needs to meet the moment’s needs. Citicoline is a critically important nutrient that the brain requires to support the mental energy, memory, focus, motor speed, and attention it must have to complete not only routine daily tasks, but to perform complex activities as well.

Unfortunately, this nutrient is not always available at the levels the brain needs, especially as individuals age, or are exerting themselves both physically and mentally. A clinically studied form of citicoline can provide what a healthy brain needs to perform well. In recent years, consumers are more health conscious, and better educated, and thus are looking for science-driven ingredients that can address multiple needs.

What is citicoline, and what does it do?

Citicoline is a naturally occurring nutrient found in the brain. It increases an important substance called phosphatidylcholine that is critical for healthy brain function. Cognizin® Citicoline is a clinically studied form of citicoline that can supply the brain with the nutrition it needs to stay sharp. Unlike other cognitive health ingredients, Cognizin® provides brain performance as well as more comprehensive brain health support overtime.

Citicoline and energy

Energy reserves play a very important role in healthy brain function. The first vital benefit of Citicoline is its ability to help support the brain's energy-producing centers. While the brain makes up only 2% of a person’s body weight, it consumes roughly 20% of the body’s energy when at rest. When performing difficult mental activities, the brain needs even more energy. Clinical research has shown that citicoline supports the health of mitochondria, the powerhouses within cells that actually produce the brain’s energy (*1). Healthy mitochondrial function results in higher levels of ATP—the body’s main energy storage molecule—in brain cells.

Why Cognizin® Citicoline?

Cognizin®, an innovative branded form of citicoline, is unlike artificial stimulants that ramp up energy and attention levels only to have those levels come crashing down later. Cognizin® provides nutritional support that helps fuel mental processes and enhance focus and concentration.

Scientific studies show how Cognizin® Citicoline supports cognitive function and performance.

The brain is constantly being attacked by various factors of our lifestyle including environmental pollution, internal toxicity, stress, and a lack of proper diet and nutrients. Citicoline may help combat the ravages of these effects by stimulating the nervous system process to maintain optimum sustainability of the molecular environment of the brain enabling a body to retain its ability to think cognitively and improve focus and attention.

One study on Cognizin® Citicoline's effect on focus and attention started with middle-aged women taking 250mg of Cognizin® daily (1,2), and exhibited a decrease in omission and commission errors, thus exhibiting how citicoline can support focus and attention when performing physical tasks.

Cognizin researchYou can read more about this study here.   

Cognizin® Citicoline has also been studied to show:

  • Scientific studies have indicated that citicoline is an effective aid for maintaining normal cognitive function with aging (*1,3).
  • Additional studies point to the ability of citicoline to act as an antioxidant in preserving normal healthy visual function (*1,4).
  • Citicoline protects neural tissue from the ravages of free radical damage(*1).
Healthy brain function is essential to quality of life. As many individuals are dealing with ongoing post-pandemic stress, brain fog and simply burnout, addressing cognitive health is top of mind. Click here to find Cognizin® in many high quality products.

Cognizin® is backed by Kyowa Hakko Bio Co., LTD. Kyowa is an international health ingredient manufacturer and a world leader in the development, manufacturing and marketing of nutraceuticals, pharmaceuticals and food products. Part of Kyowa’s dedication to ongoing scientific research, quality management and consumer education, the Cognizin® brand leads the way in clinical brain research. 

Education opportunity

Ingredients for mental wellness were discussed in depth at the Naturally Informed virtual event Stress and Mental Wellness: Mastering the Market on September 20-22, 2022. Dr. Citrolo covered the latest research during the talk A Potent Brain Health Nutrient and Nootropic for Optimizing Overall Cognitive Health. Register here to view on demand.

References
1.  *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
2. McGlade E. et al. Improved Attentional Performance Following Citicoline Administration in Healthy Adult Women. Food and Nutrition Sciences. 2012;3:769-773.
3.  Qureshi ND, I, et. al. Citicoline: A Novel Therapeutic Agent with Neuroprotective, Neuromodulatory, and Neurogenerative Properties, 2010; Natural Medicine Journal. 2(6); 11
4.  Grieb, P, et. al. Citicoline: A Food Beneficial for Patients Suffering from or Threated with Glaucoma, 2016; Frontiers in Aging Neuroscience. doi: 10.3389/fnagi.2016.00073
    Education Center
    KEYWORDS #NaturallyInformed ATP brain health Citicoline cognitive health Cognizin Kyowa Hakko USA Mental Wellness Naturally Informed nootropic Phosphatidylcholine stress
    • Related Articles

      Cognitive health: Still top of mind for consumers?

      #NaturallyInformed Keynote Educates on Importance of Omega-3s for Cognitive Health

      AlphaWave® L-Theanine: Clinical Validation for Stress, Focus, and Cognitive Support

    Danielle citrolo

    Dr. Citrolo is a registered pharmacist, and she provides scientific and regulatory support to Kyowa‘s customers in the U.S., Canada, and Latin America. She holds degrees in biochemistry and chemistry from North Carolina State University and a Doctor of Pharmacy from Albany College of Pharmacy, NY.

    People news microphone orange and blue laptop icon

    Experts in the natural products industry share their insights on top trending topics, research, and industry news and events.

    *These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

    Recommended For You
    Latest Publication
    Screenshot_2026-05-26_at_7.47.16_AM.jpg
    June/July 2026
    CovHeart.jpg
    2026 Deep Dive Cardiovascular Health
    Screenshot_2026-04-16_at_11.51.39_AM.png
    May 2026
    CovMi26.jpg
    2026 Mastering the Microbiome Market
    Most Popular
    • GettyImages-2260827018.jpg

      Karnataka High Court Issues Interim Stay on Ashwagandha Leaf Ban

      By Richard Ortega, Associate Editor, WholeFoods Magazine
      May 20, 2026
    • Anaheim Convention Center hosted four days of innovation, education, networking, and trendspotting at Expo West 2026.

      Expo West 2026 Trend Report: Innovation, Transparency & Functional Wellness

      By WholeFoods Magazine Staff
      May 26, 2026
    • Fostering mental wellness.

      The Pillars of Mental Resilience

      By Jennifer Joseph
      June 1, 2026

    WholeFoods Magazine is your one-stop resource for health and nutrition articles. We provide important information regarding industry news, research, and trends.

    The Magazine

    • Current Issue
    • Subscribe
    • Renew
    • Change of Address

    Information

    • Source Directory
    • Helpful Resources
    • Job Finder

    About Us

    • About Us
    • Contact Us
    • Advertise

    Social

    NOTE: WholeFoods Magazine is a business-to-business publication. Information on this site should not be considered medical advice or a way to diagnose or treat any disease or illness. Always seek the advice of a medical professional before making lifestyle changes, including taking a dietary supplement. The opinions expressed by contributors and experts quoted in articles are not necessarily those of the publisher or editors of WholeFoods.

    © Copyright 2026 WFC, Inc. All Rights Reserved.
    Privacy PolicyTerms